FMF-01-086-2 shows dose dependent inhibition of pAurora A (Aurora A substrate) and pH3 S10 (Aurora B substrate) in HCT116 cells. FMF-01-086-2 effects on cell cycle are consistent with selective on-target inhibition.
MedKoo Cat#: 465024
Name: FMF-01-086-2
CAS#: 2135622-31-8
Chemical Formula: C30H27N7O3
Exact Mass: 533.2175
Molecular Weight: 533.59
Elemental Analysis: C, 67.53; H, 5.10; N, 18.38; O, 9.00
The following data is based on the product molecular weight 533.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
