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MedKoo Cat#: 585304 | Name: UR 12633

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UR 12633 is an antagonist of platelet-activating factor that is effective in protecting against changes in most shock markers.

Chemical Structure

UR 12633
UR 12633
CAS#179912-83-5

Theoretical Analysis

MedKoo Cat#: 585304

Name: UR 12633

CAS#: 179912-83-5

Chemical Formula: C27H27N3O

Exact Mass: 409.2154

Molecular Weight: 409.53

Elemental Analysis: C, 79.19; H, 6.65; N, 10.26; O, 3.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
UR 12633; UR12633; UR-12633
IUPAC/Chemical Name
4-Piperidineacetonitrile, 1-(1-oxo-3,3-diphenylpropyl)-alpha-3-pyridinyl-
InChi Key
BGZWWLNNRCYROI-UHFFFAOYSA-N
InChi Code
InChI=1S/C27H27N3O/c28-19-26(24-12-7-15-29-20-24)23-13-16-30(17-14-23)27(31)18-25(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-12,15,20,23,25-26H,13-14,16-18H2
SMILES Code
N#CC(C1=CC=CN=C1)C2CCN(C(CC(C3=CC=CC=C3)C4=CC=CC=C4)=O)CC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 409.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Giral M, Balsa D, Ferrando R, Merlos M, Garcia-Rafanell J, Forn J. Effects of UR-12633, a new antagonist of platelet-activating factor, in rodent models of endotoxic shock. Br J Pharmacol. 1996 Jul;118(5):1223-31. PubMed PMID: 8818347; PubMed Central PMCID: PMC1909590.