MedKoo Cat#: 465013 | Name: ITF3756
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ITF3756 is a selective histone deacetylase 6 (HDAC6) inhibitor bearing a pentaheterocyclic scaffold.

Chemical Structure

ITF3756
ITF3756
CAS#2247608-27-9

Theoretical Analysis

MedKoo Cat#: 465013

Name: ITF3756

CAS#: 2247608-27-9

Chemical Formula: C13H11N5O2S

Exact Mass: 301.0633

Molecular Weight: 301.32

Elemental Analysis: C, 51.82; H, 3.68; N, 23.24; O, 10.62; S, 10.64

Price and Availability

Size Price Availability Quantity
25mg USD 350.00 2 Weeks
50mg USD 550.00 2 Weeks
100mg USD 950.00 2 Weeks
1g USD 3,650.00 2 Weeks
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Related CAS #
2247608-27-9;
Synonym
ITF3756; ITF-3756; ITF 3756
IUPAC/Chemical Name
N-hydroxy-4-((5-(thiophen-2-yl)-1H-tetrazol-1-yl)methyl)benzamide
InChi Key
UFUGFWWXDWPEQE-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H11N5O2S/c19-13(15-20)10-5-3-9(4-6-10)8-18-12(14-16-17-18)11-2-1-7-21-11/h1-7,20H,8H2,(H,15,19)
SMILES Code
ONC(C(C=C1)=CC=C1CN2C(C3=CC=CS3)=NN=N2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 301.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Novel Benzohydroxamate-Based Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitors Bearing a Pentaheterocyclic Scaffold: Design, Synthesis, and Biological Evaluation Barbara VerganiGiovanni SandroneMattia MarchiniChiara RipamontiEdoardo CellupicaElisabetta GalbiatiGianluca CapriniGianfranco PavichGiulia PorroIlaria RocchioMaria LattanzioMarcello PezzutoMalgorzata SkorupskaPaola CordellaPaolo PaganiPietro PozziRoberta PomaricoDaniela ModenaFlavio LeoniRaffaella PeregoGianluca FossatiChristian SteinkühlerAndrea Stevenazzi* Journal of Medicinal Chemistry, Articles ASAP (Article)Subscribed Access Publication Date (Web):November 11, 2019.