Eledoisin is an undecapeptide tachykinin that acts as a potent agonist of neurokinin receptors, especially NK1 and NK2, which mediate smooth muscle contraction and sensory neurotransmission. It binds these G protein-coupled receptors, activating phospholipase C and increasing intracellular calcium, leading to vasodilation, pain signaling, and muscle contraction. Isolated from the octopus Eledone moschata, eledoisin is widely used in research on neuropeptide signaling, inflammation, and pain.
MedKoo Cat#: 574089
Name: Eledoisin
CAS#: 69-25-0 (free base)
Chemical Formula: C54H85N13O15S
Exact Mass: 1187.6009
Molecular Weight: 1188.41
Elemental Analysis: C, 54.58; H, 7.21; N, 15.32; O, 20.19; S, 2.70
The following data is based on the product molecular weight 1,188.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
