UT-34 | CAS#2168525-92-4

MedKoo Cat#: 408048 | Name: UT-34

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UT-34 is a selective androgen receptor degrader (SARD) ligand.

Chemical Structure

UT-34

CAS#2168525-92-4

Theoretical Analysis

MedKoo Cat#: 408048

Name: UT-34

CAS#: 2168525-92-4

Chemical Formula: C15H12F4N4O2

Exact Mass: 356.0896

Molecular Weight: 356.28

Elemental Analysis: C, 50.57; H, 3.40; F, 21.33; N, 15.73; O, 8.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

UT-34; UT 34; UT34;

IUPAC/Chemical Name

(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-fluoro-1H-pyrazol-1-yl)-2-hydroxy-2-methylpropanamide

InChi Key

YDRMSDHDYRAUBR-AWEZNQCLSA-N

InChi Code

InChI=1S/C15H12F4N4O2/c1-14(25,8-23-7-10(16)6-21-23)13(24)22-11-3-2-9(5-20)12(4-11)15(17,18)19/h2-4,6-7,25H,8H2,1H3,(H,22,24)/t14-/m0/s1

SMILES Code

O=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)[C@@](C)(O)CN2N=CC(F)=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 356.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Selective androgen receptor degrader (SARD) ligands and methods of use thereof By Narayanan, Ramesh; Miller, Duane D.; Ponnusamy, Thamarai; Hwang, Dong-Jin; He, Yali From U.S. Pat. Appl. Publ. (2019), US 20190060280 A1 20190228. 2. Selective androgen receptor degrader (SARD) ligands and methods of use thereof By Narayanan, Ramesh; Miller, Duane D.; Ponnusamy, Thamarai; Hwang, Dong-Jin; He, Yali From U.S. Pat. Appl. Publ. (2019), US 20190015387 A1 20190117. 3. Preparation of N-aryl 3-heteroaryl-2-hydroxyalkanamides as selective androgen receptor degrader (SARD) ligands and methods of use thereof By Narayanan, Ramesh; Miller, Duane D.; Ponnusamy, Thamarai; Hwang, Dong-Jin; He, Yali From U.S. Pat. Appl. Publ. (2018), US 20180273487 A1 20180927. 4. Preparation of N-aryl 3-heteroaryl-2-hydroxyalkanamides as selective androgen receptor degrader (SARD) ligands and methods of use thereof By Narayanan, Ramesh; Miller, Duane; Ponnusamy, Thamarai; Hwang, Dong-Jin; He, Yali From PCT Int. Appl. (2017), WO 2017214634 A1 20171214.