VUF5834 | CAS#860002-95-5 | inverse agonist at CXCR3

MedKoo Cat#: 561756 | Name: VUF5834

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VUF5834 is a full inverse agonist at CXCR3 N3.35A.

Chemical Structure

VUF5834

CAS#860002-95-5

Theoretical Analysis

MedKoo Cat#: 561756

Name: VUF5834

CAS#: 860002-95-5

Chemical Formula: C31H41N5O2

Exact Mass: 515.3260

Molecular Weight: 515.70

Elemental Analysis: C, 72.20; H, 8.01; N, 13.58; O, 6.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

VUF5834; VUF-5834; VUF 5834;

IUPAC/Chemical Name

N-(1-(3-(4-Cyanophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-N-(2-(dimethylamino)ethyl)decanamide

InChi Key

KTSFPXCHLDGJCF-UHFFFAOYSA-N

InChi Code

InChI=1S/C31H41N5O2/c1-5-6-7-8-9-10-11-16-29(37)35(22-21-34(3)4)24(2)30-33-28-15-13-12-14-27(28)31(38)36(30)26-19-17-25(23-32)18-20-26/h12-15,17-20,24H,5-11,16,21-22H2,1-4H3

SMILES Code

CCCCCCCCCC(N(C(C(N1C2=CC=C(C#N)C=C2)=NC3=C(C=CC=C3)C1=O)C)CCN(C)C)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 515.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Verzijl D, Storelli S, Scholten DJ, Bosch L, Reinhart TA, Streblow DN, Tensen CP, Fitzsimons CP, Zaman GJ, Pease JE, de Esch IJ, Smit MJ, Leurs R. Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors. J Pharmacol Exp Ther. 2008 May;325(2):544-55. doi: 10.1124/jpet.107.134783. Epub 2008 Feb 12. PubMed PMID: 18270317; PubMed Central PMCID: PMC3659174.