MedKoo Cat#: 572663 | Name: VUN77173
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

VUN77173, also known as Benzenedimethanamine-diethylamine, is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

VUN77173
VUN77173
CAS#71277-17-3 (free base)

Theoretical Analysis

MedKoo Cat#: 572663

Name: VUN77173

CAS#: 71277-17-3 (free base)

Chemical Formula: C16H38Cl6N6

Exact Mass: 344.2455

Molecular Weight: 527.22

Elemental Analysis: C, 36.45; H, 7.27; Cl, 40.34; N, 15.94

Price and Availability

Size Price Availability Quantity
50mg USD 700.00
500mg USD 1,500.00
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Related CAS #
71277-15-1 (6 HCl) 71277-17-3 (free base)
Synonym
VUN77173; VUN-77173; VUN 77173; Benzenedimethanamine-diethylamine;
IUPAC/Chemical Name
1,4-Benzenedimethanamine, N,N,N',N'-tetrakis(2-aminoethyl)-, hexahydrochloride
InChi Key
VDUFVNNSJZDNFJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H32N6.6ClH/c17-5-9-21(10-6-18)13-15-1-2-16(4-3-15)14-22(11-7-19)12-8-20;;;;;;/h1-4H,5-14,17-20H2;6*1H
SMILES Code
NCCN(CC1=CC=C(CN(CCN)CCN)C=C1)CCN.[H]Cl.[H]Cl.[H]Cl.[H]Cl.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>96% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 527.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Boni FI, Prezotti FG, Cury BS. Gellan gum microspheres crosslinked with trivalent ion: effect of polymer and crosslinker concentrations on drug release and mucoadhesive properties. Drug Dev Ind Pharm. 2016 Aug;42(8):1283-90. doi: 10.3109/03639045.2015.1125915. Epub 2016 Jan 29. PubMed PMID: 26616390. 2: Van Haute D, Longmate JM, Berlin JM. Controlled Assembly of Biocompatible Metallic Nanoaggregates Using a Small Molecule Crosslinker. Adv Mater. 2015 Sep 16;27(35):5158-64. doi: 10.1002/adma.201501602. Epub 2015 Jul 24. PubMed PMID: 26208123; PubMed Central PMCID: PMC4567412. 3: Rao Z, Sasaki M, Taguchi T. Development of amphiphilic, enzymatically-degradable PEG-peptide conjugate as cell crosslinker for spheroid formation. Colloids Surf B Biointerfaces. 2013 Jan 1;101:223-7. doi: 10.1016/j.colsurfb.2012.06.033. Epub 2012 Jul 4. PubMed PMID: 23010023.