MedKoo Cat#: 574061 | Name: BTD-TRPC5 activator
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BTD is a selective TRPC5 activator with selectivity for TRPC5 over other TRP channels. BTD also activates TRPC1:5 and TRPC4:5 heteromers.

Chemical Structure

BTD-TRPC5 activator
BTD-TRPC5 activator
CAS#896684-04-1

Theoretical Analysis

MedKoo Cat#: 574061

Name: BTD-TRPC5 activator

CAS#: 896684-04-1

Chemical Formula: C24H33N3O4S

Exact Mass: 459.2192

Molecular Weight: 459.61

Elemental Analysis: C, 62.72; H, 7.24; N, 9.14; O, 13.92; S, 6.98

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
25mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
BTD; BTD-TRPC5 activator;
IUPAC/Chemical Name
N-(3-(adamantan-1-yloxy)propyl)-3-(6-methyl-1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)propanamide
InChi Key
YXADKMPRWFBOHW-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H33N3O4S/c1-16-3-4-21-20(9-16)26-22(27-32(21,29)30)5-6-23(28)25-7-2-8-31-24-13-17-10-18(14-24)12-19(11-17)15-24/h3-4,9,17-19H,2,5-8,10-15H2,1H3,(H,25,28)(H,26,27)
SMILES Code
CC1=CC=C2C(NC(CCC(=O)NCCCOC34CC5CC(CC(C5)C3)C4)=N[S]2(=O)=O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 459.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Beckmann H, Richter J, Hill K, Urban N, Lemoine H, Schaefer M. A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels. Cell Calcium. 2017 Sep;66:10-18. doi: 10.1016/j.ceca.2017.05.012. Epub 2017 Jun 2. PubMed PMID: 28807145.