MedKoo Cat#: 558789 | Name: Sulfo-Cyanine 5 NHS Ester
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulfo-Cyanine 5 NHS Ester is a water soluble amine reactive red emitting fluorescent dye.Used for the labeling of various amine containing molecules in aqueous phase without use of any organic co-solvent. Useful for the labeling of proteins which denature in the presence of organic co-solvents, as well as for proteins with low solubility.

Chemical Structure

Sulfo-Cyanine 5 NHS Ester
Sulfo-Cyanine 5 NHS Ester
CAS#2230212-27-6 (sodium)

Theoretical Analysis

MedKoo Cat#: 558789

Name: Sulfo-Cyanine 5 NHS Ester

CAS#: 2230212-27-6 (sodium)

Chemical Formula: C36H40N3NaO10S2

Exact Mass: 761.2053

Molecular Weight: 761.84

Elemental Analysis: C, 56.76; H, 5.29; N, 5.52; Na, 3.02; O, 21.00; S, 8.42

Price and Availability

Size Price Availability Quantity
5mg USD 550.00 2 Weeks
25mg USD 1,250.00 2 Weeks
50mg USD 2,150.00 2 Weeks
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Related CAS #
937739-58-7 (inner salt) 2230212-27-6 (sodium)
Synonym
Sulfo-Cy5-NHS Ester; Sulfo-Cyanine5 NHS Ester;
IUPAC/Chemical Name
Potassium 1-[6-(2,5-dioxopyrrolidin-1-yloxy)-6-oxohexyl]-3,3-dimethyl-2-[(1E,3E,5E)-5-(1,3,3- trimethyl-5-sulfonatoindolin-2-ylidene)penta-1,3-dienyl]-3H-indolium-5-sulfonate
InChi Key
JYLBFAAZKFROET-UHFFFAOYSA-M
InChi Code
InChI=1S/C36H41N3O10S2.Na/c1-35(2)26-22-24(50(43,44)45)15-17-28(26)37(5)30(35)12-8-6-9-13-31-36(3,4)27-23-25(51(46,47)48)16-18-29(27)38(31)21-11-7-10-14-34(42)49-39-32(40)19-20-33(39)41;/h6,8-9,12-13,15-18,22-23H,7,10-11,14,19-21H2,1-5H3,(H-,43,44,45,46,47,48);/q;+1/p-1
SMILES Code
CC(C1=CC(S(=O)([O-])=O)=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(ON4C(CCC4=O)=O)=O)C5=CC=C(S(=O)([O-])=O)C=C5C3(C)C.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 761.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Nieto-Orellana, A.; Li, H.; Rosiere, R.; Wauthoz, N..; Williams, H.; Monteiro, C.J.; Bosquillon, C.; Childerhouse, N.; Keegan, G.; Coghlan, D.; Mantovani, G.; Stolnik, S. Targeted PEG-poly(glutamic acid) complexes for inhalation protein delivery to the lung. Journal of Controlled Release, in press. doi: 10.1016/j.jconrel.2019.10.012 2. Ji, W.; Smith, P.N.; Koepsel, R.R.; Andersen, J.D.; Baker, S.L.; Zhang, L.; Carmali, S.; Myerson, J.W.; Muzykantov, V.; Russell, A.J. Erythrocytes as Carriers of Immunoglobulin-Based Therapeutics. Acta Biomaterialia, in press. doi: 10.1016/j.actbio.2019.10.027 3. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, in press. doi: 10.1021/acsabm.9b00811 4. Sameshima, T.; Yukawa, T.; Hirozane, Y.; Yoshikawa, M.; Katoh, T.; Hara, H.; Yogo, T.; Miyahisa, I.; Okuda, T.; Miyamoto, M.; Naven, R. Small-scale panel comprising diverse gene family targets to evaluate compound promiscuity. Chemical Research in Toxicology, in press. doi: 10.1021/acs.chemrestox.9b00128