MedKoo Cat#: 558784 | Name: Cyanine7 NHS ester
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

The structure of Cyanine7 features rigidized design of central polymethyne chain. This molecular reinforcement allows to increase quantum yield by 20% compared with parent structure, increasing fluorescence brightness. NIR fluorophores can be used to take advantage of near infrared window of biological tissues - increased transparency of tissues in this spectral region allows to carry out in vivo imaging. This reagent can be utilized to produce Cyanine7-labeled biomolecules for subsequent use in various in vivo research, and drug design related experiments.

Chemical Structure

Cyanine7 NHS ester
Cyanine7 NHS ester
CAS#2408482-09-5 (BF4)

Theoretical Analysis

MedKoo Cat#: 558784

Name: Cyanine7 NHS ester

CAS#: 2408482-09-5 (BF4)

Chemical Formula: C41H48BF4N3O4

Exact Mass: 0.0000

Molecular Weight: 733.66

Elemental Analysis: C, 67.12; H, 6.59; B, 1.47; F, 10.36; N, 5.73; O, 8.72

Price and Availability

Size Price Availability Quantity
5mg USD 550.00 2 Weeks
25mg USD 1,450.00 2 Weeks
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Related CAS #
1432019-64-1 (chloride) 1432466-81-3 (without anion) 2408482-09-5 (BF4)
Synonym
Cy7 NHS ester; Cy 7 NHS ester; Cy7-NHS ester; Cyanine7 NHS ester; Cyanine 7 NHS ester; Cyanine7NHS ester;
IUPAC/Chemical Name
1‐{6‐[(2,5‐dioxopyrrolidin‐1‐yl)oxy]‐6‐oxohexyl}‐ 3,3‐dimethyl‐2‐[(E)‐2‐[(3E)‐3‐{2‐[(2E)‐1,3,3‐ trimethyl‐2,3‐dihydro‐1H‐indol‐2‐ ylidene]ethylidene}cyclohex‐1‐en‐1‐yl]ethenyl]‐3H‐ indol‐1‐ium tetrafluoroborate
InChi Key
MNKUQMKZCXWMOK-UHFFFAOYSA-N
InChi Code
InChI=1S/C41H48N3O4.BF4/c1-40(2)31-16-8-10-18-33(31)42(5)35(40)23-21-29-14-13-15-30(28-29)22-24-36-41(3,4)32-17-9-11-19-34(32)43(36)27-12-6-7-20-39(47)48-44-37(45)25-26-38(44)46;2-1(3,4)5/h8-11,16-19,21-24,28H,6-7,12-15,20,25-27H2,1-5H3;/q+1;-1
SMILES Code
CC1(C)/C(N(C)C2=C1C=CC=C2)=C\C=C3C=C(/C=C/C4=[N+](CCCCCC(ON5C(CCC5=O)=O)=O)C6=C(C=CC=C6)C4(C)C)CCC\3.F[B-](F)(F)F
Appearance
Dark green solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 733.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Poreba, M.; Groborz, K.; Rut, W.; Pore, M.; Snipas, S.J.; Vizovisek, M.; Turk, B.; Kuhn, P.; Drag, M.; Salvesen, G.S. The Activome: multiplexed probing of activity of proteolytic enzymes using mass cytometry-compatible activity-based probes (TOF-probes). bioRxiv, preprint. doi: 10.1101/775627 2.Zheng, Q.; Fang, Y.; Zeng, L.; Li, X.; Chen, H.; Song, H.; Huang, J.; Shi, S. Cytocompatible cerium oxide-mediated antioxidative stress in inhibiting ocular inflammation-associated corneal neovascularization. Journal of Materials Chemistry B, 2019, 7(43), 6759–6769. doi: 10.1039/c9tb01066a 3. Xu, C.; Yu, Y.; Sun, Y.; Kong, L.; Yang, C.; Hu, M.; Yang, T.; Zhang, J.; Hu, Q.; Zhang, Z. Transformable Nanoparticle-Enabled Synergistic Elicitation and Promotion of Immunogenic Cell Death for Triple-Negative Breast Cancer Immunotherapy. Advanced Functional Materials, 2019, 29(45), 1905213. doi: 10.1002/adfm.201905213 4. Poreba, M.; Groborz, K.; Vizovisek, M.; Maruggi, M.; Turk, D.; Turk, B.; Powis, G.; Drag, M.; Salvesen, G.S. Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples. Chemical Science, 2019, 10(36), 8461–8477. doi: 10.1039/c9sc00997c