Synonym
Decaprenylamine; 3,7-Dimethyl-2,6-octadienylamine; 3,7-dimethyl-2,6-octadien-1-amine.
IUPAC/Chemical Name
3,7-dimethyl-2,6-octadienylamine
InChi Key
AFMZGMJNKXOLEM-JXMROGBWSA-N
InChi Code
InChI=1S/C10H19N/c1-9(2)5-4-6-10(3)7-8-11/h5,7H,4,6,8,11H2,1-3H3/b10-7+
SMILES Code
NC/C=C(C)/CC/C=C(C)\C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
153.27
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Nakagawa M, Akiyama S, Yamaguchi T, Shiraishi N, Ogata J, Kuwano M. Reversal of multidrug resistance by synthetic isoprenoids in the KB human cancer cell line. Cancer Res. 1986 Sep;46(9):4453-7. PubMed PMID: 3731102.
2: Yamaguchi T, Nakagawa M, Shiraishi N, Yoshida T, Kiyosue T, Arita M, Akiyama S, Kuwano M. Overcoming drug resistance in cancer cells with synthetic isoprenoids. J Natl Cancer Inst. 1986 May;76(5):947-53. PubMed PMID: 3457980.
3: Kuwano M, Nakagawa M, Shiraishi N, Yamaguchi T, Kikuchi J, Akiyama S. Techniques to reverse or circumvent drug-resistance in vitro. Prog Clin Biol Res. 1986;223:163-71. PubMed PMID: 3809198.
4: Ikezaki K, Yamaguchi T, Miyazaki C, Ueda H, Kishiye T, Tahara Y, Koyama H, Takahashi T, Fukawa H, Komiyama S, et al. Potentiation of anticancer agents by new synthetic isoprenoids. I. Inhibition of the growth of cultured mammalian cells. J Natl Cancer Inst. 1984 Oct;73(4):895-901. PubMed PMID: 6592386.
5: Yamaguchi T, Ikezaki K, Kishiye T, Tahara Y, Koyama H, Takahasi T, Fukawa H, Komiyama S, Akiyama S, Kuwano M. Potentiation of anticancer agents by new synthetic isoprenoids. II. Inhibition of the growth of transplantable murine tumors. J Natl Cancer Inst. 1984 Oct;73(4):903-7. PubMed PMID: 6207332.