α-Cyano-4-hydroxycinnamic acid | CAS# 28166-41-8 | MCT1 inhibitor

MedKoo Cat#: 574011 | Name: α-Cyano-4-hydroxycinnamic acid

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

α-Cyano-4-hydroxycinnamic acid is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate transport in rat heart mitochondria. It is commonly used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications.

Chemical Structure

α-Cyano-4-hydroxycinnamic acid

CAS#28166-41-8

Theoretical Analysis

MedKoo Cat#: 574011

Name: α-Cyano-4-hydroxycinnamic acid

CAS#: 28166-41-8

Chemical Formula: C10H7NO3

Exact Mass: 189.0426

Molecular Weight: 189.17

Elemental Analysis: C, 63.49; H, 3.73; N, 7.40; O, 25.37

Price and Availability

Size	Price	Availability	Quantity
2g	USD 400.00
10g	USD 600.00

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Related CAS #

No Data

Synonym

α-CHCA, α-Cyano-4-hydroxycinnamic acid, CHC

IUPAC/Chemical Name

2-cyano-3-(4-hydroxyphenyl)-2-propenoic acid

InChi Key

AFVLVVWMAFSXCK-VMPITWQZSA-N

InChi Code

InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+

SMILES Code

OC1=CC=C(/C=C(C(O)=O)\C#N)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

λmax: 242, 344 nm

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 189.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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