Swalpamycin | CAS#112008-27-2 | antibiotic

MedKoo Cat#: 585189 | Name: Swalpamycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Swalpamycin is a macrolide antibiotic.

Chemical Structure

Swalpamycin

CAS#112008-27-2

Theoretical Analysis

MedKoo Cat#: 585189

Name: Swalpamycin

CAS#: 112008-27-2

Chemical Formula: C37H56O14

Exact Mass: 724.3670

Molecular Weight: 724.84

Elemental Analysis: C, 61.31; H, 7.79; O, 30.90

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Swalpamycin

IUPAC/Chemical Name

Oxacyclohexadeca-3,11,13-triene-2,10-dione, 15-(((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxy)methyl)-6-(((4S,5R,6R,7S,9R)-6-hydroxy-4,9-dimethyl-2-oxo-1,3,8-trioxaspiro(4.5)dec-7-yl)oxy)-5,7,9,16-tetramethyl-, (3E,5S,6S,7S,9R,11E,13E,15R,16R)-

InChi Key

AAUZLHJDJNJJDM-KGNKUWBDSA-N

InChi Code

InChI=1S/C37H56O14/c1-19-14-15-28(39)47-23(5)26(18-45-34-32(44-9)31(43-8)29(40)24(6)48-34)12-10-11-13-27(38)20(2)16-21(3)30(19)50-35-33(41)37(17-22(4)46-35)25(7)49-36(42)51-37/h10-15,19-26,29-35,40-41H,16-18H2,1-9H3/b12-10+,13-11+,15-14+/t19-,20+,21-,22+,23+,24+,25-,26+,29+,30+,31+,32+,33-,34+,35-,37-/m0/s1

SMILES Code

O=C(/C=C/[C@H](C)[C@@H](O[C@H](O[C@H](C)C1)[C@H](O)[C@]21[C@H](C)OC(O2)=O)[C@@H](C)C[C@H]3C)O[C@H](C)[C@@H](CO[C@H]4[C@@H]([C@@H]([C@@H]([C@@H](C)O4)O)OC)OC)/C=C/C=C/C3=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 724.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Franco CM, Gandhi JN, Chatterjee S, Ganguli BN. Swalpamycin, a new macrolide antibiotic. I. Taxonomy of the producing organism, fermentation, isolation and biological activity. J Antibiot (Tokyo). 1987 Oct;40(10):1361-7. PubMed PMID: 3680001. 2: Chatterjee S, Reddy GC, Franco CM, Rupp RH, Ganguli BN, Fehlhaber HW, Kogler H. Swalpamycin, a new macrolide antibiotic. II. Structure elucidation. J Antibiot (Tokyo). 1987 Oct;40(10):1368-74. PubMed PMID: 3680002. 3: Wang CX, Ding R, Jiang ST, Tang JS, Hu D, Chen GD, Lin F, Hong K, Yao XS, Gao H. Aldgamycins J-O, 16-Membered Macrolides with a Branched Octose Unit from Streptomycetes sp. and Their Antibacterial Activities. J Nat Prod. 2016 Oct 28;79(10):2446-2454. Epub 2016 Sep 30. PubMed PMID: 27690254.