MedKoo Cat#: 532923 | Name: PSB-1901 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PSB-1901 is a novel highly potent and selective A2B adenosine receptor (A2BAR) antagonist with >10 000-fold selectivity versus all other AR subtypes.

Chemical Structure

PSB-1901 HCl
PSB-1901 HCl
CAS#PSB-1901 HCl

Theoretical Analysis

MedKoo Cat#: 532923

Name: PSB-1901 HCl

CAS#: PSB-1901 HCl

Chemical Formula: C24H26BrClN6O4S

Exact Mass: 0.0000

Molecular Weight: 609.92

Elemental Analysis: C, 47.26; H, 4.30; Br, 13.10; Cl, 5.81; N, 13.78; O, 10.49; S, 5.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Synonym
PSB-1901; PSB 1901; PSB1901; PSB-1901 HCl; PSB-1901 hydrochloride
IUPAC/Chemical Name
8-(4-((4-(4-Bromophenyl)piperazin-1-yl)sulfonyl)phenyl)-1-propylxanthine hydrochloride
InChi Key
NTTSVBHTAHTIMJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H25BrN6O4S.ClH/c1-2-11-31-23(32)20-22(28-24(31)33)27-21(26-20)16-3-9-19(10-4-16)36(34,35)30-14-12-29(13-15-30)18-7-5-17(25)6-8-18;/h3-10H,2,11-15H2,1H3,(H,26,27)(H,28,33);1H
SMILES Code
O=C(N1CCC)NC2=C(NC(C3=CC=C(S(=O)(N4CCN(C5=CC=C(Br)C=C5)CC4)=O)C=C3)=N2)C1=O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 609.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jiang J, Seel CJ, Temirak A, Namasivayam V, Arridu A, Schabikowski J, Baqi Y, Hinz S, Hockemeyer J, Müller CE. A(2B) Adenosine Receptor Antagonists with Picomolar Potency. J Med Chem. 2019 Apr 15. doi: 10.1021/acs.jmedchem.9b00071. [Epub ahead of print] PubMed PMID: 30835463.