Synonym
Dieugenol; Bis-Eugenol; Dehydrodieugenol
IUPAC/Chemical Name
3,3'-dimethoxy-5,5'-di-2-propen-1-yl-[1,1'-biphenyl]-2,2'-diol
InChi Key
KETPSFSOGFKJJY-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H22O4/c1-5-7-13-9-15(19(21)17(11-13)23-3)16-10-14(8-6-2)12-18(24-4)20(16)22/h5-6,9-12,21-22H,1-2,7-8H2,3-4H3
SMILES Code
OC1=C(OC)C=C(CC=C)C=C1C2=CC(CC=C)=CC(OC)=C2O
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
326.39
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Grecco SS, Jerz G, Lago JHG, Jones PG. Crystal structure of De-hydro- dieugenol B methyl ether, a neolignan from Nectandra leucantha Nees and Mart (Lauraceae). Acta Crystallogr E Crystallogr Commun. 2018 Mar 9;74(Pt 4):518-521. doi: 10.1107/S2056989018003717. PMID: 29765758; PMCID: PMC5946980.
2: Fakhrudin N, Ladurner A, Atanasov AG, Heiss EH, Baumgartner L, Markt P, Schuster D, Ellmerer EP, Wolber G, Rollinger JM, Stuppner H, Dirsch VM. Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma. Mol Pharmacol. 2010 Apr;77(4):559-66. doi: 10.1124/mol.109.062141. Epub 2010 Jan 11. PMID: 20064974; PMCID: PMC3523390.
3: Ogata M, Hoshi M, Urano S, Endo T. Antioxidant activity of eugenol and related monomeric and dimeric compounds. Chem Pharm Bull (Tokyo). 2000 Oct;48(10):1467-9. doi: 10.1248/cpb.48.1467. PMID: 11045452.
