Solasonine | CAS#19121-58-5 | anti-fungal

MedKoo Cat#: 592696 | Name: Solasonine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Solasonine is weakly anti-fungal.

Chemical Structure

Solasonine

CAS#19121-58-5

Theoretical Analysis

MedKoo Cat#: 592696

Name: Solasonine

CAS#: 19121-58-5

Chemical Formula: C45H73NO16

Exact Mass: 883.4929

Molecular Weight: 884.07

Elemental Analysis: C, 61.14; H, 8.32; N, 1.58; O, 28.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Solasonine; NSC 82149; NSC82149; NSC82149

IUPAC/Chemical Name

beta-D-Galactopyranoside, (3beta,22alpha,25R)-spirosol-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-3))- (9CI)

InChi Key

QCTMYNGDIBTNSK-XEAAVONHSA-N

InChi Code

InChI=1S/C45H73NO16/c1-19-8-13-45(46-16-19)20(2)30-27(62-45)15-26-24-7-6-22-14-23(9-11-43(22,4)25(24)10-12-44(26,30)5)57-42-39(61-40-36(54)34(52)31(49)21(3)56-40)38(33(51)29(18-48)59-42)60-41-37(55)35(53)32(50)28(17-47)58-41/h6,19-21,23-42,46-55H,7-18H2,1-5H3/t19-,20+,21+,23+,24-,25+,26+,27+,28-,29-,30+,31+,32-,33+,34-,35+,36-,37-,38+,39-,40+,41+,42-,43+,44+,45-/m1/s1

SMILES Code

C[C@@H]1CC[C@]2(O[C@H]3C[C@H]4[C@@H]5CC=C6C[C@@H](O[C@@H]7O[C@@H]([C@@H]([C@@H]([C@H]7O[C@@H]8O[C@H]([C@@H]([C@H]([C@H]8O)O)O)C)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O)O)O)CO)O)CO)CC[C@@]6([C@H]5CC[C@@]4([C@H]3[C@@H]2C)C)C)NC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 884.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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Antiproliferative activity of Solanum lycocarpum alkaloidic extract and their constituents, solamargine and solasonine, in tumor cell lines. J Nat Med. 2014 Jan;68(1):236-41. doi: 10.1007/s11418-013-0757-0. Epub 2013 Mar 10. PubMed PMID: 23475509. 5: Sánchez-Mata MC, Yokoyama WE, Hong YJ, Prohens J. Alpha-solasonine and alpha-solamargine contents of gboma (Solanum macrocarpon L.) and scarlet (Solanum aethiopicum L.) eggplants. J Agric Food Chem. 2010 May 12;58(9):5502-8. doi: 10.1021/jf100709g. PubMed PMID: 20397650. 6: Hall CA, Hobby T, Cipollini M. Efficacy and mechanisms of alpha-solasonine-and alpha-solamargine-induced cytolysis on two strains of Trypanosoma cruzi. J Chem Ecol. 2006 Nov;32(11):2405-16. PubMed PMID: 17001530. 7: Lezama-Dávila CM, McChesney JD, Bastos JK, Miranda MA, Tiossi RF, da Costa Jde C, Bentley MV, Gaitan-Puch SE, Isaac-Márquez AP. 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PubMed PMID: 23576350. 15: Tiossi RF, Da Costa JC, Miranda MA, Praça FS, McChesney JD, Bentley MV, Bastos JK. In vitro and in vivo evaluation of the delivery of topical formulations containing glycoalkaloids of Solanum lycocarpum fruits. Eur J Pharm Biopharm. 2014 Sep;88(1):28-33. doi: 10.1016/j.ejpb.2014.01.010. Epub 2014 Feb 6. PubMed PMID: 24509413. 16: Wang X, Zou S, Lan YL, Xing JS, Lan XQ, Zhang B. Solasonine inhibits glioma growth through anti-inflammatory pathways. Am J Transl Res. 2017 Sep 15;9(9):3977-3989. eCollection 2017. PubMed PMID: 28979674; PubMed Central PMCID: PMC5622243. 17: Miranda MA, Magalhães LG, Tiossi RF, Kuehn CC, Oliveira LG, Rodrigues V, McChesney JD, Bastos JK. Evaluation of the schistosomicidal activity of the steroidal alkaloids from Solanum lycocarpum fruits. Parasitol Res. 2012 Jul;111(1):257-62. doi: 10.1007/s00436-012-2827-8. Epub 2012 Jan 27. PubMed PMID: 22281548. 18: Roddick JG, Weissenberg M, Leonard AL. 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