CM 6606 | CAS#65352-97-8 | antimalarial

MedKoo Cat#: 585142 | Name: CM 6606

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CM 6606 is an indolo (3,2-c) quinoline-N-oxide that possesses antimalarial activity.

Chemical Structure

CM 6606

CAS#65352-97-8

Theoretical Analysis

MedKoo Cat#: 585142

Name: CM 6606

CAS#: 65352-97-8

Chemical Formula: C21H22ClN3O2

Exact Mass: 383.1401

Molecular Weight: 383.88

Elemental Analysis: C, 65.71; H, 5.78; Cl, 9.23; N, 10.95; O, 8.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CM 6606; CM6606; CM-6606

IUPAC/Chemical Name

11H-Indolo(3,2-c)quinoline-11-propanamine, 3-chloro-8-methoxy-N,N-dimethyl-, 5-oxide

InChi Key

YWXLUYYYULQCMS-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H22ClN3O2/c1-23(2)9-4-10-24-19-8-6-15(27-3)12-17(19)18-13-25(26)20-11-14(22)5-7-16(20)21(18)24/h5-8,11-13H,4,9-10H2,1-3H3

SMILES Code

CN(C)CCCN1C2=C(C3=C[N+]([O-])=C4C=C(Cl)C=CC4=C31)C=C(OC)C=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 383.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Peters W, Robinson BL, Mutambu SL, Warhurst DC, Ellis DS, Tovey DG. The chemotherapy of rodent malaria. XLIV. Studies on the mode of action of CM 6606, an indolo (3,2-c) quinoline N-oxide. Ann Trop Med Parasitol. 1989 Feb;83(1):1-10. PubMed PMID: 2688575. 2: Peters W, Robinson BL. The chemotherapy of rodent malaria.XLIII. Indolo (3,2-c) quinoline-N-oxides. Ann Trop Med Parasitol. 1988 Oct;82(5):423-7. PubMed PMID: 3077021. 3: Olliaro P, Castelli F, Caligaris S, Druilhe P, Carosi G. Ultrastructure of Plasmodium falciparum "in vitro". II. Morphological patterns of different quinolines effects. Microbiologica. 1989 Jan;12(1):15-28. PubMed PMID: 2654570.