SEP-0372814 | CAS#1516896-09-5 | PDE10 inhibitor

MedKoo Cat#: 555623 | Name: SEP-0372814

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SEP-0372814, also known as PDE10-IN-1, is a PDE10 inhibitor.

Chemical Structure

SEP-0372814

CAS#1516896-09-5

Theoretical Analysis

MedKoo Cat#: 555623

Name: SEP-0372814

CAS#: 1516896-09-5

Chemical Formula: C21H19N7

Exact Mass: 369.1702

Molecular Weight: 369.43

Elemental Analysis: C, 68.28; H, 5.18; N, 26.54

Price and Availability

Size	Price	Availability
50mg	USD 450.00	2 Weeks
100mg	USD 750.00	2 Weeks
200mg	USD 1,250.00	2 Weeks
500mg	USD 2,450.00	2 Weeks
1g	USD 3,450.00	2 Weeks
2g	USD 6,450.00	2 Weeks

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

1516896-09-5 1516895-53-6

Synonym

SEP-0372814; SEP0372814; SEP 0372814; PDE10-IN-1; PDE10-IN1; PDE10-IN 1;

IUPAC/Chemical Name

rel-2-[(1R,2R)-2-(5,8-Dimethyl[1,2,4]triazolo[1,5-a]pyrazin-2-yl)cyclopropyl]-3-methylimidazo[2,1-f][1,6]naphthyridine

InChi Key

ZLHNYULRKIEGAY-HZPDHXFCSA-N

InChi Code

InChI=1S/C21H19N7/c1-11-10-23-12(2)20-25-19(26-28(11)20)16-9-15(16)18-13(3)27-8-6-17-14(21(27)24-18)5-4-7-22-17/h4-8,10,15-16H,9H2,1-3H3/t15-,16-/m1/s1

SMILES Code

CC1=C([C@H]2[C@H](C3=NN4C(C(C)=NC=C4C)=N3)C2)N=C5C6=C(N=CC=C6)C=CN51

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

PDE10-IN-1 is a potent PDE10-IN-1 inhibitor extracted from Patent WO 2013192273 A1, for treating CNS and metabolic disorders.

In vitro activity:

To be determined

In vivo activity:

To be determined

Preparing Stock Solutions

The following data is based on the product molecular weight 369.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

To be determined

In vitro protocol:

To be determined

In vivo protocol:

To be determined

Campbell, John Emmerson, et al. Preparation of heteroaryl compounds as PDE-10 inhibitors for treating CNS and metabolic disorders. Patent WO 2013192273 A1 20131227. https://patents.google.com/patent/WO2013192273A1