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MedKoo Cat#: 573940 | Name: Adrogolide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Adrogolide acts as a selective dopamine receptor D1 agonist. It was developed as a possible treatment for Parkinson's disease and cocaine addiction. It has mainly been used as its diacetate ester prodrug adrogolide.

Chemical Structure

Adrogolide
CAS#171752-56-0 (free base)

Theoretical Analysis

MedKoo Cat#: 573940

Name: Adrogolide

CAS#: 171752-56-0 (free base)

Chemical Formula: C22H25NO4S

Exact Mass: 399.1504

Molecular Weight: 399.51

Elemental Analysis: C, 66.14; H, 6.31; N, 3.51; O, 16.02; S, 8.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
171752-56-0 (free base) 166591-11-3 (HCl)
Synonym
Adrogolide; A-93431.1; A93431.1; A 93431.1; DAS 431; DAS-431; DAS431; ABT 431;ABT-431;ABT431;
IUPAC/Chemical Name
(5aR, 11bS) 4,5,5a,6,7,11b-Hexahydro-2-propylbenzo(f)thienol(2,3c)quinoline-9,10-diol diacetate (ester)
InChi Key
KTEBZVJGMARTOQ-GCJKJVERSA-N
InChi Code
1S/C22H25NO4S/c1-4-5-15-9-17-21(28-15)11-23-18-7-6-14-8-19(26-12(2)24)20(27-13(3)25)10-16(14)22(17)18/h8-10,18,22-23H,4-7,11H2,1-3H3/t18-,22+/m1/s1
SMILES Code
C(=O)(C)Oc1cc2c(CC[C@@H]3[C@@H]2c2cc(CCC)sc2CN3)cc1OC(=O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 399.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gleason SD, Witkin JM. Effects of dopamine D1 receptor full agonists in rats trained to discriminate SKF 38393. Behav Pharmacol. 2004 Feb;15(1):85-9. PubMed PMID: 15075630.