Quinestradol | CAS#1169-79-5 | estrogen

MedKoo Cat#: 585070 | Name: Quinestradol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Quinestradol is a synthetic estrogen and estrogen ether.

Chemical Structure

Quinestradol

CAS#1169-79-5

Theoretical Analysis

MedKoo Cat#: 585070

Name: Quinestradol

CAS#: 1169-79-5

Chemical Formula: C23H32O3

Exact Mass: 356.2351

Molecular Weight: 356.51

Elemental Analysis: C, 77.49; H, 9.05; O, 13.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Quinestradol; Colpovis; Colpovister; Pentovis

IUPAC/Chemical Name

3-(Cyclopentyloxy)estra-1,3,5(10)-triene-16alpha,17beta-diol

InChi Key

ODYKCPYPRCJXLY-PZORDLPLSA-N

InChi Code

InChI=1S/C23H32O3/c1-23-11-10-18-17-9-7-16(26-15-4-2-3-5-15)12-14(17)6-8-19(18)20(23)13-21(24)22(23)25/h7,9,12,15,18-22,24-25H,2-6,8,10-11,13H2,1H3/t18-,19-,20+,21-,22+,23+/m1/s1

SMILES Code

C[C@@]12[C@@H](O)[C@H](O)C[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC5CCCC5)=C4)[C@@]3([H])CC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 356.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Liu Q, Qin J, Chen Q, Wang D, Shi D. Fertility control of Rattus nitidus using quinestrol: effects on reproductive organs and social behavior. Integr Zool. 2013 Apr;8 Suppl 1:9-17. doi: 10.1111/j.1749-4877.2012.00296.x. Epub 2012 Oct 31. Erratum in: Integr Zool. 2016 Mar;11(2):173. PubMed PMID: 23621467. 2: Katzenellenbogen BS. Biology and receptor interactions of estriol and estriol derivatives in vitro and in vivo. J Steroid Biochem. 1984 Apr;20(4B):1033-7. PubMed PMID: 6727348. 3: Bruni G, Rossi GL, Celasco G, Falconi G. [Effects of estriol and quinestradol administered to pregnant rats on the fetal sex differentiation]. Ann Ostet Ginecol Med Perinat. 1975 Mar-Apr;96(2):83-90. Italian. PubMed PMID: 1220592. 4: Judge TG. The use of quinestradol in elderly incontinent women, a preliminary report. Gerontol Clin (Basel). 1969;11(3):159-64. PubMed PMID: 4890404. 5: Beaton D. A comparative trial of quinestradol and ethinyl oestradiol. Br J Clin Pract. 1967 May;21(5):241-3. PubMed PMID: 6046407. 6: Eckstein P, Greig M, Butt WR. The induction of withdrawal bleeding with quinestradol (pentovis) in spayed monkeys, and some observations on its excretion and that of oestriol in the urine. J Endocrinol. 1967 Mar;37(3):239-44. PubMed PMID: 4960138.