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MedKoo Cat#: 573813 | Name: Betazole HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Betazole hydrochloride is a histamine H2 agonist used clinically to test gastric secretory function.

Chemical Structure

Betazole HCl
Betazole HCl
CAS#138-92-1 (HCl)

Theoretical Analysis

MedKoo Cat#: 573813

Name: Betazole HCl

CAS#: 138-92-1 (HCl)

Chemical Formula: C5H11Cl2N3

Exact Mass: 183.0330

Molecular Weight: 184.06

Elemental Analysis: C, 32.63; H, 6.02; Cl, 38.52; N, 22.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
105-20-4 (free base) 138-92-1 (HCl)
Synonym
Ametazole dihydrochloride, Betazole dihydrochloride, Betazole hydrochloride, Betazole HCl, Gastramine, Histalog, Histimin
IUPAC/Chemical Name
1H-Pyrazole-3-ethanamine, dihydrochloride
InChi Key
BUXCUOWXTOKEMQ-UHFFFAOYSA-N
InChi Code
1S/C5H9N3.2ClH/c6-3-1-5-2-4-7-8-5;;/h2,4H,1,3,6H2,(H,7,8);2*1H
SMILES Code
Cl.Cl.c1(CCN)cc[nH]n1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 184.06 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Noguchi Y, Ito M, Katsumi K, Yokoyama Y, Yasue N, Miyamoto T, Joh T, Takeuchi T. Effects of cyclic nucleotides, betazole hydrochloride and acetylcholine on pepsinogen secretion from isolated rabbit gastric mucosa. Gastroenterol Jpn. 1986 Apr;21(2):129-34. PubMed PMID: 3011576. 2: Spitz IM, Novis BH, Ebert R, Trestian S, LeRoith D, Creutzfeldt W. Betazole-induced GIP secretion is not mediated by gastric HCl. Metabolism. 1982 Apr;31(4):380-2. PubMed PMID: 7078422. 3: Nilsell K, Ewerth S. The acid secretory response to betazole and insulin hypoglycemia after selective proximal vagotomy for duodenal ulcer. Acta Chir Scand. 1981;147(6):431-4. PubMed PMID: 7034435.