Oxamisole | CAS# 99258-56-7 (free base) | immunoregulator

MedKoo Cat#: 585037 | Name: Oxamisole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oxamisole is an immunoregulator that has immunorestorative effects on T-cells.

Chemical Structure

Oxamisole

CAS#99258-56-7 (free base)

Theoretical Analysis

MedKoo Cat#: 585037

Name: Oxamisole

CAS#: 99258-56-7 (free base)

Chemical Formula: C15H20N2O2

Exact Mass: 260.1525

Molecular Weight: 260.34

Elemental Analysis: C, 69.20; H, 7.74; N, 10.76; O, 12.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

99258-55-6 (HCl); 99258-56-7 (free base)

Synonym

Oxamisole; Oxamisol; PR 879-317A

IUPAC/Chemical Name

Imidazo(1,2-a)pyridine, 2,3,5,6,7,8-hexahydro-8,8-dimethoxy-2-phenyl-

InChi Key

DWIKEPVFPTUJQU-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H20N2O2/c1-18-15(19-2)9-6-10-17-11-13(16-14(15)17)12-7-4-3-5-8-12/h3-5,7-8,13H,6,9-11H2,1-2H3

SMILES Code

COC1(OC)C2=NC(C3=CC=CC=C3)CN2CCC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 260.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Radov LA, Kamp D, Trusso LA, Sloane D, Julien RP, Clemens CM, Murray RJ. The immunological profile of a new immunomodulatory agent, oxamisole. Int J Immunopharmacol. 1988;10(5):609-18. PubMed PMID: 3263341. 2: Warren RP, Sidwell RW, Huffman JH, Call EW, Healey MC, Johnston AV, Radov LA, Murray RJ, Kinsolving CR. Effect of oxamisole on immune parameters of mice infected with murine hepatitis. Int J Immunopharmacol. 1990;12(6):625-30. PubMed PMID: 2177037. 3: Sidwell RW, Morrey JD, Okleberry KM, Burger RA, Warren RP. Immunomodulator effects on the Friend virus infection in genetically defined mice. Ann N Y Acad Sci. 1993 Jun 23;685:432-46. PubMed PMID: 8363251. 4: Sidwell RW, Huffman JH, Call EW, Warren RP, Radov LA, Murray RJ. Inhibition of murine hepatitis virus infections by the immunomodulator 2,3,5,6,7,8-hexahydro-2-phenyl-8,8-dimethoxy-imidazo[1,2a]pyridine (PR-879-317A). Antimicrob Agents Chemother. 1987 Jul;31(7):1130-4. PubMed PMID: 2821891; PubMed Central PMCID: PMC174883. 5: Warren RP, Healey MC, Johnston AV, Sidwell RW, Radov LA, Murray RJ, Kinsolving CR. PR 879-317A enhances in vitro immune activity of peripheral blood mononuclear cells from patients with Down syndrome. Int J Immunopharmacol. 1987;9(8):919-26. PubMed PMID: 2962955.