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MedKoo Cat#: 565675 | Name: 2-Ethoxystypandrone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

2-Ethoxystypandrone is a novel potent natural stat3 signaling inhibitor from polygonum cuspidatum, inhibiting cell growth and inducing apoptosis of hcc cells and hcc cancer stem cells.

Chemical Structure

2-Ethoxystypandrone
2-Ethoxystypandrone
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 565675

Name: 2-Ethoxystypandrone

CAS#: N/A

Chemical Formula: C15H14O5

Exact Mass: 274.0841

Molecular Weight: 274.27

Elemental Analysis: C, 65.69; H, 5.15; O, 29.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
2-Ethoxystypandrone
IUPAC/Chemical Name
6-Acetyl-5-hydroxy-2-ethoxy-7-methylnaphthalene-1,4-dione
InChi Key
HHPDGVKSXLTKLE-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H14O5/c1-4-20-11-6-10(17)13-9(14(11)18)5-7(2)12(8(3)16)15(13)19/h5-6,19H,4H2,1-3H3
SMILES Code
O=C1C(OCC)=CC(C2=C1C=C(C)C(C(C)=O)=C2O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 274.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li W, Zhang Q, Chen K, Sima Z, Liu J, Yu Q, Liu J. 2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells. BMC Complement Altern Med. 2019 Feb 1;19(1):38. doi: 10.1186/s12906-019-2440-9. PubMed PMID: 30709346; PubMed Central PMCID: PMC6359800.