MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 565657 | Name: MA-0204 sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MA-0204 is a novel highly potent and selective pparδ modulator

Chemical Structure

MA-0204 sodium
MA-0204 sodium
CAS#2095128-17-7 (free acid)

Theoretical Analysis

MedKoo Cat#: 565657

Name: MA-0204 sodium

CAS#: 2095128-17-7 (free acid)

Chemical Formula: C25H26F3N2NaO4

Exact Mass: 0.0000

Molecular Weight: 498.48

Elemental Analysis: C, 60.24; H, 5.26; F, 11.43; N, 5.62; Na, 4.61; O, 12.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
2095128-30-4 2095128-17-7 (free acid)
Synonym
MA-0204; MA 0204; MA0204; MA-0204 sodium;
IUPAC/Chemical Name
sodium (R)-3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)methyl)phenoxy)hexanoate
InChi Key
DEMPZEPJIMOVJT-UNTBIKODSA-M
InChi Code
InChI=1S/C25H27F3N2O4.Na/c1-17(14-23(31)32)6-5-13-33-22-8-4-3-7-20(22)16-30-18(2)15-29-24(30)19-9-11-21(12-10-19)34-25(26,27)28;/h3-4,7-12,15,17H,5-6,13-14,16H2,1-2H3,(H,31,32);/q;+1/p-1/t17-;/m1./s1
SMILES Code
O=C([O-])C[C@H](C)CCCOC1=CC=CC=C1CN2C(C)=CN=C2C3=CC=C(OC(F)(F)F)C=C3.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 498.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lagu B, Kluge AF, Tozzo E, Fredenburg R, Bell EL, Goddeeris MM, Dwyer P, Basinski A, Senaiar RS, Jaleel M, Tiwari NK, Panigrahi SK, Krishnamurthy NR, Takahashi T, Patane MA. Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD). ACS Med Chem Lett. 2018 Jul 31;9(9):935-940. doi: 10.1021/acsmedchemlett.8b00287. eCollection 2018 Sep 13. Erratum in: ACS Med Chem Lett. 2019 Apr 24;10(6):1013. PubMed PMID: 30258544; PubMed Central PMCID: PMC6142063.