AM-92016 is an oxypropanolamine analogue of sotalol, has been shown to possess Class III anti-arrhythmic properties in-vitro at concentrations showing 1000 times more potency than sotalol. AM 92016 exhibited proarrhythmic rather than antiarrhythmic activity when administered in-vivo to either guinea-pigs or pigs.
MedKoo Cat#: 555585
Name: AM-92016 HCl
CAS#: 133229-11-5 (HCl)
Chemical Formula: C19H25Cl3N2O4S
Exact Mass: 0.0000
Molecular Weight: 483.83
Elemental Analysis: C, 47.17; H, 5.21; Cl, 21.98; N, 5.79; O, 13.23; S, 6.63
The following data is based on the product molecular weight 483.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
