MedKoo Cat#: 573753 | Name: Alprostadil isopropyl ester
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Alprostadil isopropyl ester is a drug used in the treatment of impotence.

Chemical Structure

Alprostadil isopropyl ester
Alprostadil isopropyl ester
CAS#217182-28-0 (isopropyl ester)

Theoretical Analysis

MedKoo Cat#: 573753

Name: Alprostadil isopropyl ester

CAS#: 217182-28-0 (isopropyl ester)

Chemical Formula: C23H40O5

Exact Mass: 396.2876

Molecular Weight: 396.57

Elemental Analysis: C, 69.66; H, 10.17; O, 20.17

Price and Availability

Size Price Availability Quantity
1mg USD 450.00 2 Weeks
5mg USD 1,250.00 2 Weeks
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Synonym
Alprostadil impurity J , Alprostadil isopropyl ester, Prostaglandin E1 isopropyl ester
IUPAC/Chemical Name
1-Methylethyl 7-((1R,2R,3R)-3-hydroxy-2-((1E,3S)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)heptanoate
InChi Key
IVJLDARWZNUIAU-WUDJJVMMSA-N
InChi Code
1S/C23H40O5/c1-4-5-8-11-18(24)14-15-20-19(21(25)16-22(20)26)12-9-6-7-10-13-23(27)28-17(2)3/h14-15,17-20,22,24,26H,4-13,16H2,1-3H3/b15-14+/t18-,19+,20+,22+/m0/s1
SMILES Code
CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)OC(C)C)O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 396.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hanchanale V, Eardley I. Alprostadil for the treatment of impotence. Expert Opin Pharmacother. 2014 Feb;15(3):421-8. doi: 10.1517/14656566.2014.873789. Epub 2013 Dec 26. Review. PubMed PMID: 24369066. 2: Lea AP, Bryson HM, Balfour JA. Intracavernous alprostadil. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in erectile dysfunction. Drugs Aging. 1996 Jan;8(1):56-74. Review. PubMed PMID: 8785470.