MedKoo Cat#: 584948 | Name: GSK-J5 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GSK J5 HCl is the inactive isomer of GSK J4.

Chemical Structure

GSK-J5 HCl
GSK-J5 HCl
CAS#1797983-32-4 (HCl)

Theoretical Analysis

MedKoo Cat#: 584948

Name: GSK-J5 HCl

CAS#: 1797983-32-4 (HCl)

Chemical Formula: C24H28ClN5O2

Exact Mass: 453.1932

Molecular Weight: 453.97

Elemental Analysis: C, 63.50; H, 6.22; Cl, 7.81; N, 15.43; O, 7.05

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
50mg USD 1,450.00 2 Weeks
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Synonym
GSK J5 HCl; GSKJ5 HCl; GSK-J5 HCl; GSK-J5 hydrochloride
IUPAC/Chemical Name
N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester hydrochloride
InChi Key
QQHQMHJAOKADED-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H27N5O2.ClH/c1-2-31-23(30)9-13-26-21-16-22(28-24(27-21)20-8-5-12-25-17-20)29-14-10-18-6-3-4-7-19(18)11-15-29;/h3-8,12,16-17H,2,9-11,13-15H2,1H3,(H,26,27,28);1H
SMILES Code
O=C(OCC)CCNC1=NC(C2=CC=CN=C2)=NC(N3CCC4=CC=CC=C4CC3)=C1.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 453.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Kruidenier et al (2012) A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 488 404 PMID: 22842901