MedKoo Cat#: 573610 | Name: Cinnamic acid, hydrazide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cinnamic acid, hydrazide is an unsaturated carboxylic acid and precursor to aspartame via enzyme-catalysed amination to phenylalanine. Cinnamic acid may be useful in prevention or treatment of Diabetes through various mechanism of actions including stimulation of insulin secretion, improvement of pancreatic β-cell functionality, inhibition of hepatic gluconeogenesis, enhanced glucose uptake, increased insulin signaling pathway, delay of carbohydrate digestion and glucose absorption, and inhibition of protein glycation and insulin fibrillation.

Chemical Structure

Cinnamic acid, hydrazide
Cinnamic acid, hydrazide
CAS#3538-69-0

Theoretical Analysis

MedKoo Cat#: 573610

Name: Cinnamic acid, hydrazide

CAS#: 3538-69-0

Chemical Formula: C9H10N2O

Exact Mass: 162.0793

Molecular Weight: 162.19

Elemental Analysis: C, 66.65; H, 6.21; N, 17.27; O, 9.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
AI3-62695; Cinnamic acid, hydrazide; Cinnamoyl hydrazide; Cinnamoylhydrazine
IUPAC/Chemical Name
2-Propenoic acid, 3-phenyl-, hydrazide (9CI)
InChi Key
MTWDGUWQZYXGTQ-VOTSOKGWSA-N
InChi Code
1S/C9H10N2O/c10-11-9(12)7-6-8-4-2-1-3-5-8/h1-7H,10H2,(H,11,12)/b7-6+
SMILES Code
c1(\C=C\C(NN)=O)ccccc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 162.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Adisakwattana S. Cinnamic Acid and Its Derivatives: Mechanisms for Prevention and Management of Diabetes and Its Complications. Nutrients. 2017 Feb 21;9(2). pii: E163. doi: 10.3390/nu9020163. Review. PubMed PMID: 28230764; PubMed Central PMCID: PMC5331594. 2: Tang Y, Zheng M, Chen YL, Chen J, He Y. Pharmacokinetic Effects of Cinnamic Acid, Amygdalin, Glycyrrhizic Acid and Liquiritin on Ephedra Alkaloids in Rats. Eur J Drug Metab Pharmacokinet. 2017 Jun;42(3):527-535. doi: 10.1007/s13318-016-0368-8. PubMed PMID: 27514823. 3: Mielecki M, Lesyng B. Cinnamic Acid Derivatives as Inhibitors of Oncogenic Protein Kinases--Structure, Mechanisms and Biomedical Effects. Curr Med Chem. 2016;23(10):954-82. Review. PubMed PMID: 26980568.