GDC0276, also known as RG7893, is a selective, reversible, orally bioavailable small-molecule sodium channel blocker that is selective for Nav1.7, which is expressed primarily on peripheral nociceptor C-fiber neurons and is required for pain sensing in humans.
MedKoo Cat#: 555532
Name: GDC0276
CAS#: 1494581-70-2
Chemical Formula: C24H31FN2O4S
Exact Mass: 462.1989
Molecular Weight: 462.58
Elemental Analysis: C, 62.32; H, 6.76; F, 4.11; N, 6.06; O, 13.83; S, 6.93
The following data is based on the product molecular weight 462.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
