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MedKoo Cat#: 584939 | Name: Orf 17910

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Orf 17910 is a histamine H2-receptor antagonist.

Chemical Structure

Orf 17910
Orf 17910
CAS#87107-94-6

Theoretical Analysis

MedKoo Cat#: 584939

Name: Orf 17910

CAS#: 87107-94-6

Chemical Formula: C18H27N5O2S

Exact Mass: 377.1885

Molecular Weight: 377.51

Elemental Analysis: C, 57.27; H, 7.21; N, 18.55; O, 8.48; S, 8.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Orf 17910; Orf17910; Orf-17910
IUPAC/Chemical Name
1,2,5-Thiadiazole-3,4-diamine, N-(3-(3-((4-methyl-1-piperidinyl)methyl)phenoxy)propyl)-, 1-oxide
InChi Key
PPMYJUCFCTXGKV-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H27N5O2S/c1-14-6-9-23(10-7-14)13-15-4-2-5-16(12-15)25-11-3-8-20-18-17(19)21-26(24)22-18/h2,4-5,12,14H,3,6-11,13H2,1H3,(H2,19,21)(H,20,22)
SMILES Code
NC1=NS(N=C1NCCCOC2=CC=CC(CN3CCC(C)CC3)=C2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 377.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Katz LB, Scott CK, Shriver DA. Pharmacological comparison of ORF 17910, a potent, long-acting histamine H2-receptor antagonist, to cimetidine and ranitidine. J Pharmacol Exp Ther. 1986 Aug;238(2):587-93. PubMed PMID: 2874214. 2: Huang SM, Tran-Phan H. High-performance liquid chromatographic determination of a new H2 blocker (ORF 17 910) in plasma. J Chromatogr. 1987 Dec 25;423:358-64. PubMed PMID: 2895116.

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