Taclamine hydrochloride | CAS# 34061-34-2 | Biochemical

MedKoo Cat#: 573585 | Name: Taclamine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Taclamine hydrochloride is a biochemical with minor sedative properties.

Chemical Structure

Taclamine hydrochloride

CAS#34061-34-2 (HCl)

Theoretical Analysis

MedKoo Cat#: 573585

Name: Taclamine hydrochloride

CAS#: 34061-34-2 (HCl)

Chemical Formula: C21H24ClN

Exact Mass: 325.1597

Molecular Weight: 325.88

Elemental Analysis: C, 77.40; H, 7.42; Cl, 10.88; N, 4.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

34061-33-1 (free base) 34061-34-2 (HCl)

Synonym

AY 22214, AY-22,214; Taclamine HCl, Taclamine hydrochloride

IUPAC/Chemical Name

(9bS,15aS)-4,5,9b,12,13,14,15,15a-octahydro-10H-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinoline hydrochloride

InChi Key

LOSFVNFVCCXCEN-FKLPMGAJSA-N

InChi Code

InChI=1S/C21H23N.ClH/c1-2-8-17-15(6-1)11-12-16-7-5-9-18-20-10-3-4-13-22(20)14-19(17)21(16)18;/h1-2,5-9,19-20H,3-4,10-14H2;1H/t19-,20-;/m0./s1

SMILES Code

[H][C@@]12CN3[C@](CCCC3)([H])C4=CC=CC(CCC5=C2C=CC=C5)=C14.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 325.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Arribas E, Vega S, Benito C, Fernandez-Tome MP, del Rio J. Synthesis and pharmacological study of the thiophene analogue of taclamine, QM-7184, a new neuroleptic drug with potent alpha-adrenoceptor blocking activity. Arzneimittelforschung. 1983;33(10):1417-21. PubMed PMID: 6140017. 2: Pugsley TA, Lippmann W. Effects of taclamine (AY-22,214), a new psychoactive agent, on catecholamine and serotonin metabolism. Arch Int Pharmacodyn Ther. 1975 Jan;213(1):73-87. PubMed PMID: 1156020.