Captodiame hydrochloride | CAS# 904-04-1 | Anti-anxiety

MedKoo Cat#: 573582 | Name: Captodiame hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Captodiame hydrochloride is an antihistamine used as a sedative and anxiolytic. Captodiame may be helpful in preventing benzodiazepine withdrawal syndrome in people discontinuing benzodiazepine treatment.

Chemical Structure

Captodiame hydrochloride

CAS#904-04-1

Theoretical Analysis

MedKoo Cat#: 573582

Name: Captodiame hydrochloride

CAS#: 904-04-1

Chemical Formula: C21H30ClNS2

Exact Mass: 395.1508

Molecular Weight: 396.05

Elemental Analysis: C, 63.69; H, 7.64; Cl, 8.95; N, 3.54; S, 16.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

AY 55074, Captodiame HCl, Captodiame hydrochloride, Captodiamine hydrochloride, Covatin hydrochloride, Covatine, Covatix hydrochloride, N-68, Suvren

IUPAC/Chemical Name

2-(p-(Butylthio)-alpha-phenylbenzylthio)-N,N-dimethylethylamine hydrochloride

InChi Key

IQCZDPRPOLRNQX-UHFFFAOYSA-N

InChi Code

1S/C21H29NS2.ClH/c1-4-5-16-23-20-13-11-19(12-14-20)21(24-17-15-22(2)3)18-9-7-6-8-10-18;/h6-14,21H,4-5,15-17H2,1-3H3;1H

SMILES Code

c1([C@@H](c2ccccc2)SCC[NH+](C)C)ccc(SCCCC)cc1.[ClH-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 396.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Baandrup L, Ebdrup BH, Rasmussen JØ, Lindschou J, Gluud C, Glenthøj BY. Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users. Cochrane Database Syst Rev. 2018 Mar 15;3:CD011481. doi: 10.1002/14651858.CD011481.pub2. Review. PubMed PMID: 29543325. 2: PENTNEY BH, BROTHERWOOD RW. Captodiame in anxiety states in general practice. Practitioner. 1960 Aug;185:218-21. PubMed PMID: 14431646. 3: ABBOTT LG. Neurodermatoses and captodiame. Aust J Dermatol. 1960 Jun;5:187-90. PubMed PMID: 13791384.