Oxeladin | CAS#468-61-1 | antitussive

MedKoo Cat#: 584933 | Name: Oxeladin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oxeladin is an antitussive agent.

Chemical Structure

Oxeladin

CAS#468-61-1

Theoretical Analysis

MedKoo Cat#: 584933

Name: Oxeladin

CAS#: 468-61-1

Chemical Formula: C20H33NO3

Exact Mass: 335.2460

Molecular Weight: 335.49

Elemental Analysis: C, 71.60; H, 9.92; N, 4.18; O, 14.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Oxeladin; EC 207-412-1; Oxeladina; Oxeladine; Oxeladinum

IUPAC/Chemical Name

2-(2-Diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate

InChi Key

IQADUMSPOQKAAO-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H33NO3/c1-5-20(6-2,18-12-10-9-11-13-18)19(22)24-17-16-23-15-14-21(7-3)8-4/h9-13H,5-8,14-17H2,1-4H3

SMILES Code

CCC(C1=CC=CC=C1)(CC)C(OCCOCCN(CC)CC)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 335.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lartigue-Mattei C, Galmier MJ, Chabard JL, Beyssac E, Aiache JM. Determination of oxeladin in human plasma by gas chromatography--mass spectrometry. Biomed Chromatogr. 1995 Jan-Feb;9(1):32-5. PubMed PMID: 7734931. 2: DAVID A, LEITH-ROSS F, VALLANCE DK. Antitussive and other pharmacological properties of the diethylaminoethoxyethyl ester of alpha alpha-diethylphenylacetic acid, (oxeladin). J Pharm Pharmacol. 1957 Jul;9(7):446-58. PubMed PMID: 13439531. 3: El-Gindy A. High performance liquid chromatographic determination of oxeladin citrate and oxybutynin hydrochloride and their degradation products. Farmaco. 2005 Aug;60(8):689-99. PubMed PMID: 16023117. 4: Takagi K, Yuizono T, Kasé Y. [On the site of antitussive action of 2-(2-diethylaminoethoxy)ethyl alpha,alpha-diethylphenylacetate (Oxeladin)]. Yakugaku Zasshi. 1967 Aug;87(8):898-906. Japanese. PubMed PMID: 5625837. 5: Salvesen B, Haugland T. Determination of oxeladin in human sera by gas--liquid chromatography with thermionic detection. J Chromatogr. 1981 Oct 9;225(2):463-8. PubMed PMID: 7298782. 6: OZAWA H, FUKUDA H, OTSUKI I, CHIBA S. [Antitussive activity and acute toxicity of 2-(2-diethylamino-ethoxy)ethyl alpha,alpha-diethylphenylacetate (oxeladin)]. Yakugaku Zasshi. 1962 Sep;82:1314-7. Japanese. PubMed PMID: 13940888. 7: Knopp C, Korsatko W. [Determination of oxeladin citrate in drug combinations]. Pharmazie. 1982 Jan;37(1):76-7. German. PubMed PMID: 7071116. 8: Tarayre JP, Vilain P, Lauressergues H, Cauquil J, Bru M, Caillol V, Pouget G, Jougla AM, Go M. Pharmacological study of the antitussive and respiratory-analeptic properties of N-(2'-ethylpyrrolidino)diphenylacetamide hydrochloride (F 1459). Arzneimittelforschung. 1983;33(7):931-5. PubMed PMID: 6684929.