MedKoo Cat#: 565222 | Name: DM-NOFD
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF).

Chemical Structure

DM-NOFD
DM-NOFD
CAS#865488-53-5

Theoretical Analysis

MedKoo Cat#: 565222

Name: DM-NOFD

CAS#: 865488-53-5

Chemical Formula: C13H15NO5

Exact Mass: 265.0950

Molecular Weight: 265.27

Elemental Analysis: C, 58.86; H, 5.70; N, 5.28; O, 30.16

Price and Availability

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5mg USD 350.00 Back order
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Related CAS #
No Data
Synonym
DMNOFD; DM NOFD; DM-NOFD
IUPAC/Chemical Name
N-(2-Methoxy-2-oxoacetyl)-D-phenylalanine methyl ester
InChi Key
CAUUPQLNYYFMOQ-SNVBAGLBSA-N
InChi Code
InChI=1S/C13H15NO5/c1-18-12(16)10(14-11(15)13(17)19-2)8-9-6-4-3-5-7-9/h3-7,10H,8H2,1-2H3,(H,14,15)/t10-/m1/s1
SMILES Code
O=C(OC)[C@@H](CC1=CC=CC=C1)NC(C(OC)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 265.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD