MedKoo Cat#: 573542 | Name: Pildralazine dihydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pildralazine dihydrochloride is an antihypertensive.

Chemical Structure

Pildralazine dihydrochloride
Pildralazine dihydrochloride
CAS#56393-22-7 (2HCl)

Theoretical Analysis

MedKoo Cat#: 573542

Name: Pildralazine dihydrochloride

CAS#: 56393-22-7 (2HCl)

Chemical Formula: C8H17Cl2N5O

Exact Mass: 269.0810

Molecular Weight: 270.16

Elemental Analysis: C, 35.57; H, 6.34; Cl, 26.24; N, 25.92; O, 5.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
64000-73-3 (free base); 56393-22-7 (2HCl)
Synonym
Atensil, Pildralazine dihydrochloride, Pildralazine HCl, Propyldazine hydrochloride
IUPAC/Chemical Name
1-((6-hydrazinylpyridazin-3-yl)(methyl)amino)propan-2-ol dihydrochloride
InChi Key
ZEJHFYVAMIWPTN-UHFFFAOYSA-N
InChi Code
1S/C8H15N5O.2ClH/c1-6(14)5-13(2)8-4-3-7(10-9)11-12-8;;/h3-4,6,14H,5,9H2,1-2H3,(H,10,11);2*1H
SMILES Code
CC(CN(C)c1ccc(nn1)NN)O.Cl.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 270.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Noack E, Cawello W, Bonn R. Kinetic studies of the tissue binding tendency of the new vasodilator pildralazine. Arzneimittelforschung. 1987 Apr;37(4):407-9. PubMed PMID: 3606695. 2: Dorigotti L, Carpi C, Bertoli G, Mariani PL. Effects of pildralazine alone and in combination on severe hypertension and cerebrovascular lesions in saline-drinking spontaneously hypertensive rats. Arzneimittelforschung. 1984;34(8):876-9. PubMed PMID: 6541924.