Related CAS #
59512-37-7 (HCl); 60576-13-8 (free base)
Synonym
Piketoprofen hydrochloride; Piketoprofen HCl
IUPAC/Chemical Name
3-Benzoyl-alpha-methyl-N-(4-methyl-2-pyridinyl)benzeneacetamide hydrochloride
InChi Key
IPJQOSVBWMGLAM-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H20N2O2.ClH/c1-15-11-12-23-20(13-15)24-22(26)16(2)18-9-6-10-19(14-18)21(25)17-7-4-3-5-8-17;/h3-14,16H,1-2H3,(H,23,24,26);1H
SMILES Code
O=C(NC1=NC=CC(C)=C1)C(C)C2=CC=CC(C(C3=CC=CC=C3)=O)=C2.[H]Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
380.87
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Fernández-Jorge B, Goday Buján JJ, Paradela S, Mazaira M, Fonseca E. Consort photocontact dermatitis from piketoprofen. Contact Dermatitis. 2008 Feb;58(2):113-5. doi: 10.1111/j.1600-0536.2007.01183.x. PubMed PMID: 18186752.
2: Rodríguez-Lozano J, Goday Buján JJ, Del Pozo J, Fonseca E. Allergic contact dermatitis from topical piketoprofen. Contact Dermatitis. 2005 Feb;52(2):110-1. PubMed PMID: 15725293.
3: López-Abad R, Paniagua MJ, Botey E, Gaig P, Rodriguez P, Richart C. Topical dexketoprofen as a cause of photocontact dermatitis. J Investig Allergol Clin Immunol. 2004;14(3):247-9. PubMed PMID: 15552721.
4: Buján JJ, Morante JM, Güemes MG, Del Pozo Losada J, Capdevila EF. Photoallergic contact dermatitis from piketoprofen. Contact Dermatitis. 2000 Nov;43(5):315. PubMed PMID: 11016682.
5: Navarro LA, Jorro G, Morales C, Peláez A. Allergic contact dermatitis due to piketoprofen. Contact Dermatitis. 1995 Mar;32(3):181. PubMed PMID: 7774201.
6: Fabregas JL, Cucala J, Segura J, Tarrus E. Percutaneous absorption of piketoprofen in rabbits: effect of nonionic surface-active agents. Farmaco Prat. 1986 May;41(5):177-83. PubMed PMID: 3487466.