AT2433-B1 | CAS# 102622-96-8 | Antitumor

MedKoo Cat#: 573528 | Name: AT2433-B1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AT2433-B1 is an antitumor compound. Structurally, AT2433-B1 is similar to rebeccamycin --- an indolocarbazole antitumor antibiotic.

Chemical Structure

AT2433-B1

CAS#102622-96-8

Theoretical Analysis

MedKoo Cat#: 573528

Name: AT2433-B1

CAS#: 102622-96-8

Chemical Formula: C34H36N4O9

Exact Mass: 644.2482

Molecular Weight: 644.68

Elemental Analysis: C, 63.35; H, 5.63; N, 8.69; O, 22.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

AT2433-B1, AT 2433-B1

IUPAC/Chemical Name

5H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione, 12-(6-O-(2,4-dideoxy-4-(methylamino)pentopyranosyl)-4-O-methylhexopyranosyl)-12,13-dihydro-6-methyl-

InChi Key

WMXBPIZAQBGEPB-YSELHZIJSA-N

InChi Code

1S/C34H36N4O9/c1-35-18-13-45-22(12-20(18)39)46-14-21-31(44-3)29(40)30(41)34(47-21)38-19-11-7-5-9-16(19)24-26-25(32(42)37(2)33(26)43)23-15-8-4-6-10-17(15)36-27(23)28(24)38/h4-11,18,20-22,29-31,34-36,39-41H,12-14H2,1-3H3/t18-,20-,21+,22-,29+,30+,31+,34?/m0/s1

SMILES Code

c12c(c3c(cccc3)[nH]2)c2C(=O)N(C(=O)c2c2c3ccccc3[n@@]([C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO[C@@H]3OC[C@@H]([C@H](C3)O)NC)OC)O)O)c12)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 644.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Carrasco C, Facompré M, Chisholm JD, Van Vranken DL, Wilson WD, Bailly C. DNA sequence recognition by the indolocarbazole antitumor antibiotic AT2433-B1 and its diastereoisomer. Nucleic Acids Res. 2002 Apr 15;30(8):1774-81. PubMed PMID: 11937631; PubMed Central PMCID: PMC113207. 2: Golik J, Doyle TW, Krishnan B, Dubay G, Matson JA. AT2433-A1, AT2433-A2, AT2433-B1 and AT2433-B2 novel antitumor compounds produced by Actinomadura melliaura. II. Structure determination. J Antibiot (Tokyo). 1989 Dec;42(12):1784-9. PubMed PMID: 2621161.