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MedKoo Cat#: 565093 | Name: HC103A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HC103A is an inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence.

Chemical Structure

HC103A
HC103A
CAS#312595-37-2

Theoretical Analysis

MedKoo Cat#: 565093

Name: HC103A

CAS#: 312595-37-2

Chemical Formula: C18H14N2O3S

Exact Mass: 338.0725

Molecular Weight: 338.38

Elemental Analysis: C, 63.89; H, 4.17; N, 8.28; O, 14.18; S, 9.47

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CCG257424; CCG-257424; CCG 257424; HC-103A; HC 103A; HC103A; HC103-A
IUPAC/Chemical Name
N-[3-[(3-Hydroxyphenyl)carbamoyl]phenyl]thiophene-2-carboxamide
InChi Key
RFBZYRMLQURAPP-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H14N2O3S/c21-15-7-2-6-14(11-15)19-17(22)12-4-1-5-13(10-12)20-18(23)16-8-3-9-24-16/h1-11,21H,(H,19,22)(H,20,23)
SMILES Code
O=C(C1=CC=CS1)NC2=CC=CC(C(NC3=CC=CC(O)=C3)=O)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 338.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zheng H, Colvin CJ, Johnson BK, Kirchhoff PD, Wilson M, Jorgensen-Muga K, Larsen SD, Abramovitch RB. Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence. Nat Chem Biol. 2017 Feb;13(2):218-225. doi: 10.1038/nchembio.2259. Epub 2016 Dec 19. PubMed PMID: 27992879.