Synonym
Famprofazone; Geodowin; BRN 5768367; BRN-5768367; BRN5768367
IUPAC/Chemical Name
4-isopropyl-1-methyl-5-((methyl(1-phenylpropan-2-yl)amino)methyl)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
InChi Key
GNUXVOXXWGNPIV-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H31N3O/c1-18(2)23-22(17-25(4)19(3)16-20-12-8-6-9-13-20)26(5)27(24(23)28)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3
SMILES Code
O=C1N(C2=CC=CC=C2)N(C)C(CN(C)C(C)CC3=CC=CC=C3)=C1C(C)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
377.53
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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8: Shin HS, Park BB, Choi SN, Oh JJ, Hong CP, Ryu H. Identification of new urinary metabolites of famprofazone in humans. J Anal Toxicol. 1998 Jan-Feb;22(1):55-60. PubMed PMID: 9491970.
9: Neugebauer M, Khedr A, el-Rabbat N, el-Kommos M, Saleh G. Stereoselective metabolic study of famprofazone. Biomed Chromatogr. 1997 Nov-Dec;11(6):356-61. PubMed PMID: 9413615.
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13: Neugebauer M. Some new urinary metabolites of famprofazone and morazone in man. J Pharm Biomed Anal. 1984;2(1):53-60. PubMed PMID: 16867765.
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16: Cody JD. Metabolic Precursors to Amphetamine and Methamphetamine. Forensic Sci Rev. 1993 Dec;5(2):109-27. Review. PubMed PMID: 26270078.
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18: Kraemer T, Maurer HH. Toxicokinetics of amphetamines: metabolism and toxicokinetic data of designer drugs, amphetamine, methamphetamine, and their N-alkyl derivatives. Ther Drug Monit. 2002 Apr;24(2):277-89. Review. PubMed PMID: 11897973.
