MedKoo Cat#: 555477 | Name: FEMA4774
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FEMA4774, also known as S9632, is the novel T1R2/T1R3 positive allosteric modulator. FEMA4774 shows obvious enhancement of the sweetness of sucrose in sensory evaluation tests.

Chemical Structure

FEMA4774
FEMA4774
CAS#1359963-68-0

Theoretical Analysis

MedKoo Cat#: 555477

Name: FEMA4774

CAS#: 1359963-68-0

Chemical Formula: C19H25N3O4

Exact Mass: 359.1845

Molecular Weight: 359.43

Elemental Analysis: C, 63.49; H, 7.01; N, 11.69; O, 17.81

Price and Availability

Size Price Availability Quantity
25mg USD 250.00 2 Weeks
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 1,950.00 2 Weeks
1g USD 2,850.00 2 Weeks
2g USD 4,950.00 2 Weeks
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Synonym
FEMA4774; FEMA-4774; FEMA 4774; S9632; S-9632; S 9632;
IUPAC/Chemical Name
4-amino-5-(3-(isopropylamino)-2,2-dimethyl-3-oxopropoxy)-2-methylquinoline-3-carboxylic acid
InChi Key
RHXLOOCFQPJWBW-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H25N3O4/c1-10(2)21-18(25)19(4,5)9-26-13-8-6-7-12-15(13)16(20)14(17(23)24)11(3)22-12/h6-8,10H,9H2,1-5H3,(H2,20,22)(H,21,25)(H,23,24)
SMILES Code
O=C(C1=C(N)C2=C(OCC(C)(C)C(NC(C)C)=O)C=CC=C2N=C1C)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 359.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Arthur AJ, Karanewsky DS, Liu H, Chi B, Markison S. Toxicological evaluation of the flavour ingredient 4-amino-5-(3-(isopropylamino)-2,2-dimethyl-3-oxopropoxy)-2-methylquinoline-3-carb oxylic acid. Toxicol Rep. 2015 Sep 3;2:1255-1264. doi: 10.1016/j.toxrep.2015.08.012. eCollection 2015. PubMed PMID: 28962468; PubMed Central PMCID: PMC5598146.