MedKoo Cat#: 563536 | Name: Isofraxidin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Isofraxidin is an anti-bacterial, anti-oxidant, and anti-inflammatory agent. It acts by reducing the levels of tumor necrosis factor-a (TNF-a), interleukin-6 (IL-6), and prostaglandin E2 (PGE2), inhibiting cyclooxygenase-2 (COX-2) protein expression.

Chemical Structure

Isofraxidin
Isofraxidin
CAS#486-21-5

Theoretical Analysis

MedKoo Cat#: 563536

Name: Isofraxidin

CAS#: 486-21-5

Chemical Formula: C11H10O5

Exact Mass: 222.0528

Molecular Weight: 222.19

Elemental Analysis: C, 59.46; H, 4.54; O, 36.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Isofraxidin; Phytodolor;
IUPAC/Chemical Name
7-Hydroxy-6,8-dimethoxychromen-2-one
InChi Key
HOEVRHHMDJKUMZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H10O5/c1-14-7-5-6-3-4-8(12)16-10(6)11(15-2)9(7)13/h3-5,13H,1-2H3
SMILES Code
O=C1C=CC2=C(O1)C(OC)=C(O)C(OC)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 222.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li T, Ferns K, Yan ZQ, Yin SY, Kou JJ, Li D, Zeng Z, Yin L, Wang X, Bao HX, Zhou YJ, Li QH, Zhao ZY, Liu H, Liu SL. Acanthopanax senticosus: Photochemistry and Anticancer Potential. Am J Chin Med. 2016;44(8):1543-1558. Epub 2016 Nov 16. Review. PubMed PMID: 27852123. 2: Deyama T, Nishibe S, Nakazawa Y. Constituents and pharmacological effects of Eucommia and Siberian ginseng. Acta Pharmacol Sin. 2001 Dec;22(12):1057-70. Review. PubMed PMID: 11749801.