NE 58051 | CAS#104261-69-0 | inhibitor

MedKoo Cat#: 584844 | Name: NE 58051

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NE 58051 inhibits tumor cell adhesion to extracellular matrices.

Chemical Structure

NE 58051

CAS#104261-69-0

Theoretical Analysis

MedKoo Cat#: 584844

Name: NE 58051

CAS#: 104261-69-0

Chemical Formula: C8H13NO7P2

Exact Mass: 297.0167

Molecular Weight: 297.14

Elemental Analysis: C, 32.34; H, 4.41; N, 4.71; O, 37.69; P, 20.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NE 58051; NE-58051; NE58051

IUPAC/Chemical Name

Phosphonic acid, (1-hydroxy-3-(3-pyridinyl)propylidene)bis-

InChi Key

ILROXFQHACCDLA-UHFFFAOYSA-N

InChi Code

InChI=1S/C8H13NO7P2/c10-8(17(11,12)13,18(14,15)16)4-3-7-2-1-5-9-6-7/h1-2,5-6,10H,3-4H2,(H2,11,12,13)(H2,14,15,16)

SMILES Code

OC(P(O)(O)=O)(P(O)(O)=O)CCC1=CC=CN=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 297.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Fournier PG, Stresing V, Ebetino FH, Clézardin P. How do bisphosphonates inhibit bone metastasis in vivo? Neoplasia. 2010 Jul;12(7):571-8. PubMed PMID: 20651986; PubMed Central PMCID: PMC2907583. 2: Boissier S, Ferreras M, Peyruchaud O, Magnetto S, Ebetino FH, Colombel M, Delmas P, Delaissé JM, Clézardin P. Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases. Cancer Res. 2000 Jun 1;60(11):2949-54. PubMed PMID: 10850442. 3: Boissier S, Magnetto S, Frappart L, Cuzin B, Ebetino FH, Delmas PD, Clezardin P. Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices. Cancer Res. 1997 Sep 15;57(18):3890-4. PubMed PMID: 9307266.