MedKoo Cat#: 564989 | Name: ONO-8713

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ONO-8713 is a prostaglandin E receptor subtype EP1 selective antagonist.

Chemical Structure

ONO-8713
ONO-8713
CAS#209686-45-3

Theoretical Analysis

MedKoo Cat#: 564989

Name: ONO-8713

CAS#: 209686-45-3

Chemical Formula: C25H24F3NO6S

Exact Mass: 523.1276

Molecular Weight: 523.52

Elemental Analysis: C, 57.36; H, 4.62; F, 10.89; N, 2.68; O, 18.34; S, 6.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ONO8713; ONO 8713; ONO-8713
IUPAC/Chemical Name
4-[2-[N-Isobutyl-N-(2-furylsulphonyl)amino]-5-trifluoromethylphenoxymethyl] cinnamic acid; (E)-3-[4-[[2-[furan-2-ylsulfonyl(2-methylpropyl)amino]-5-(trifluoromethyl)phenoxy]methyl]phenyl]prop-2-enoic acid
InChi Key
LOQMSUDLLHPPHQ-FMIVXFBMSA-N
InChi Code
InChI=1S/C25H24F3NO6S/c1-17(2)15-29(36(32,33)24-4-3-13-34-24)21-11-10-20(25(26,27)28)14-22(21)35-16-19-7-5-18(6-8-19)9-12-23(30)31/h3-14,17H,15-16H2,1-2H3,(H,30,31)/b12-9+
SMILES Code
O=C(O)/C=C/C1=CC=C(COC2=CC(C(F)(F)F)=CC=C2N(S(=O)(C3=CC=CO3)=O)CC(C)C)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 523.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Norel X, de Montpreville V, Brink C. Vasoconstriction induced by activation of EP1 and EP3 receptors in human lung: effects of ONO-AE-248, ONO-DI-004, ONO-8711 or ONO-8713. Prostaglandins Other Lipid Mediat. 2004 Oct;74(1-4):101-12. PubMed PMID: 15560119. 2: Watanabe K, Kawamori T, Nakatsugi S, Ohta T, Ohuchida S, Yamamoto H, Maruyama T, Kondo K, Narumiya S, Sugimura T, Wakabayashi K. Inhibitory effect of a prostaglandin E receptor subtype EP(1) selective antagonist, ONO-8713, on development of azoxymethane-induced aberrant crypt foci in mice. Cancer Lett. 2000 Aug 1;156(1):57-61. PubMed PMID: 10840160.