Triprolidine hydrochloride anhydrous is a first-generation antihistamine that acts as a competitive antagonist of the H₁ histamine receptor. By blocking histamine binding, it reduces allergic responses such as nasal congestion, itching, and swelling. Its lipophilic nature allows it to cross the blood-brain barrier, leading to sedative effects commonly associated with H₁ receptor antagonists.
MedKoo Cat#: 573418
Name: Triprolidine hydrochloride anhydrous
CAS#: 550-70-9
Chemical Formula: C19H23ClN2
Exact Mass: 314.1550
Molecular Weight: 314.86
Elemental Analysis: C, 72.48; H, 7.36; Cl, 11.26; N, 8.90
The following data is based on the product molecular weight 314.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
