Eudesmol | 51317-08-9

MedKoo Cat#: 581717 | Name: Eudesmol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Eudesmol, β-Eudesmol can be used to study biochemicals found in plants. β-Eudesmol has been used in a study to investigate the chemical composition, antioxidant, antimicrobial and anti-wood-decay fungal activities of the essential oil isolated from the twigs of Taiwania cryptomerioides from Taiwan. β-Eudesmol has also been used in a study that contributed towards the discovery of new antifungal agents, by investigating the properties of the heartwood essential oils of two trees growing in New Caledonia, Callitris neocaledonica and C. sulcata (Cupressaceae).

Chemical Structure

Eudesmol

CAS#51317-08-9

Theoretical Analysis

MedKoo Cat#: 581717

Name: Eudesmol

CAS#: 51317-08-9

Chemical Formula: C15H28O

Exact Mass: 224.2140

Molecular Weight: 224.39

Elemental Analysis: C, 80.29; H, 12.58; O, 7.13

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Eudesmol; UNII-EGP3DXQ87.

IUPAC/Chemical Name

2-((2R,4aR,8R,8aS)-4a,8-dimethyldecahydronaphthalen-2-yl)propan-2-ol

InChi Key

YJHVMPKSUPGGPZ-GUIRCDHDSA-N

InChi Code

InChI=1S/C15H28O/c1-11-6-5-8-15(4)9-7-12(10-13(11)15)14(2,3)16/h11-13,16H,5-10H2,1-4H3/t11-,12-,13+,15-/m1/s1

SMILES Code

C[C@@H]1CCC[C@]2([C@H]1C[C@@H](CC2)C(C)(C)O)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 224.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Aati H, El-Gamal A, Kayser O. Chemical composition and biological activity of the essential oil from the root of Jatropha pelargoniifolia Courb. native to Saudi Arabia. Saudi Pharm J. 2019 Jan;27(1):88-95. doi: 10.1016/j.jsps.2018.09.001. Epub 2018 Sep 11. PubMed PMID: 30662311; PubMed Central PMCID: PMC6323148. 2: Guo SS, Wang Y, Pang X, Geng ZF, Cao JQ, Du SS. Seven herbs against the stored product insect: Toxicity evidence and the active sesquiterpenes from Atractylodes lancea. Ecotoxicol Environ Saf. 2019 Mar;169:807-813. doi: 10.1016/j.ecoenv.2018.11.095. Epub 2018 Nov 29. PubMed PMID: 30597779. 3: Ohara K, Misaizu A, Kaneko Y, Fukuda T, Miyake M, Miura Y, Okamura H, Yajima J, Tsuda A. β-Eudesmol, an Oxygenized Sesquiterpene, Reduces the Increase in Saliva 3-Methoxy-4-Hydroxyphenylglycol After the "Trier Social Stress Test" in Healthy Humans: A Randomized, Double-Blind, Placebo-Controlled Cross-Over Study. Nutrients. 2018 Dec 20;11(1). pii: E9. doi: 10.3390/nu11010009. PubMed PMID: 30577513. 4: Martviset P, Chaijaroenkul W, Muhamad P, Na-Bangchang K. Bioactive constituents isolated from Atractylodes lancea (Thunb.) DC. rhizome exhibit synergistic effect against cholangiocarcinoma cell. J Exp Pharmacol. 2018 Oct 25;10:59-64. doi: 10.2147/JEP.S177032. eCollection 2018. PubMed PMID: 30498376; PubMed Central PMCID: PMC6207387. 5: Shao H, Jiang Y, Pan F, Xie J, Qi J, Xiao H, Chen Y. Chemical composition, UV/vis absorptivity, and antioxidant activity of essential oils from bark and leaf of phoebe zhennan S. K. Lee & F. N. Wei. Nat Prod Res. 2018 Nov 29:1-4. doi: 10.1080/14786419.2018.1504047. [Epub ahead of print] PubMed PMID: 30488722. 6: Blerot B, Martinelli L, Prunier C, Saint-Marcoux D, Legrand S, Bony A, Sarrabère L, Gros F, Boyer N, Caissard JC, Baudino S, Jullien F. Functional Analysis of Four Terpene Synthases in Rose-Scented Pelargonium Cultivars (Pelargonium × hybridum) and Evolution of Scent in the Pelargonium Genus. Front Plant Sci. 2018 Nov 2;9:1435. doi: 10.3389/fpls.2018.01435. eCollection 2018. PubMed PMID: 30483274; PubMed Central PMCID: PMC6240891. 7: Wang B, Ge L, Mo J, Su L, Li Y, Yang K. Essential oils and ethanol extract from Camellia nitidissima and evaluation of their biological activity. J Food Sci Technol. 2018 Dec;55(12):5075-5081. doi: 10.1007/s13197-018-3446-x. Epub 2018 Oct 6. PubMed PMID: 30483003; PubMed Central PMCID: PMC6233457. 8: Hattan JI, Shindo K, Sasaki T, Misawa N. Isolation and Functional Characterization of New Terpene Synthase Genes from Traditional Edible Plants. J Oleo Sci. 2018;67(10):1235-1246. doi: 10.5650/jos.ess18163. PubMed PMID: 30305556. 9: Hashim GM, Almasaudi SB, Azhar E, Al Jaouni SK, Harakeh S. Biological activity of Cymbopogon schoenanthus essential oil. Saudi J Biol Sci. 2017 Nov;24(7):1458-1464. doi: 10.1016/j.sjbs.2016.06.001. Epub 2016 Jun 13. PubMed PMID: 30294213; PubMed Central PMCID: PMC6169510. 10: Yusufoglu HS, Tabanca N, Bernier UR, Li AY, Salkini MA, Alqasoumi SI, Demirci B. Mosquito and tick repellency of two Anthemis essential oils from Saudi Arabia. Saudi Pharm J. 2018 Sep;26(6):860-864. doi: 10.1016/j.jsps.2018.03.012. Epub 2018 Mar 27. PubMed PMID: 30202228; PubMed Central PMCID: PMC6128710. 11: Moon PD, Han NR, Lee JS, Kim HY, Hong S, Kim HJ, Yoo MS, Kim HM, Jeong HJ. β-eudesmol inhibits thymic stromal lymphopoietin through blockade of caspase-1/NF-κB signal cascade in allergic rhinitis murine model. Chem Biol Interact. 2018 Oct 1;294:101-106. doi: 10.1016/j.cbi.2018.08.026. Epub 2018 Aug 24. PubMed PMID: 30148989. 12: Ohara K, Katayama M, Nagai K. β-eudesmol, an oxygenized sesquiterpene, affects efferent adrenal sympathetic nerve activity via transient receptor potential ankyrin 1 in rats. Neurosci Lett. 2018 Sep 25;684:18-24. doi: 10.1016/j.neulet.2018.06.057. Epub 2018 Jun 30. PubMed PMID: 29966754. 13: Danielli LJ, Pippi B, Duarte JA, Maciel AJ, Lopes W, Machado MM, Oliveira LFS, Vainstein MH, Teixeira ML, Bordignon SAL, Fuentefria AM, Apel MA. Antifungal mechanism of action of Schinus lentiscifolius Marchand essential oil and its synergistic effect in vitro with terbinafine and ciclopirox against dermatophytes. J Pharm Pharmacol. 2018 Sep;70(9):1216-1227. doi: 10.1111/jphp.12949. Epub 2018 Jun 28. PubMed PMID: 29956331. 14: Srijiwangsa P, Ponnikorn S, Na-Bangchang K. Effect of β-Eudesmol on NQO1 suppression-enhanced sensitivity of cholangiocarcinoma cells to chemotherapeutic agents. BMC Pharmacol Toxicol. 2018 Jun 19;19(1):32. doi: 10.1186/s40360-018-0223-4. PubMed PMID: 29914576; PubMed Central PMCID: PMC6006851. 15: de Souza TDS, Ferreira MFDS, Menini L, Souza JRCL, Bernardes CO, Ferreira A. Chemotype diversity of Psidium guajava L. Phytochemistry. 2018 Sep;153:129-137. doi: 10.1016/j.phytochem.2018.06.006. Epub 2018 Jun 15. PubMed PMID: 29913321. 16: Kuś PM, Okińczyc P, Jakovljević M, Jokić S, Jerković I. Development of supercritical CO(2) extraction of bioactive phytochemicals from black poplar (Populus nigra L.) buds followed by GC-MS and UHPLC-DAD-QqTOF-MS. J Pharm Biomed Anal. 2018 Sep 5;158:15-27. doi: 10.1016/j.jpba.2018.05.041. Epub 2018 May 25. PubMed PMID: 29852355. 17: Garzoli S, Laghezza Masci V, Turchetti G, Pesci L, Tiezzi A, Ovidi E. Chemical investigations of male and female leaf extracts from Schinus molle L. Nat Prod Res. 2018 May 29:1-4. doi: 10.1080/14786419.2018.1480624. [Epub ahead of print] PubMed PMID: 29842798. 18: Jiang T, Li K, Liu H, Yang L. Extraction of biomedical compounds from the wood of Pterocarpus macarocarpus Kurz heartwood. Pak J Pharm Sci. 2018 May;31(3):913-918. PubMed PMID: 29716873. 19: Monggoot S, Kulsing C, Wong YF, Pripdeevech P. Incubation of Aquilaria subintegra with Microbial Culture Supernatants Enhances Production of Volatile Compounds and Improves Quality of Agarwood Oil. Indian J Microbiol. 2018 Jun;58(2):201-207. doi: 10.1007/s12088-018-0717-1. Epub 2018 Mar 8. PubMed PMID: 29651179; PubMed Central PMCID: PMC5891480. 20: Chen WT, Chen Y, Cui B, Li XQ, Fan YH, Wang XH, An R. [Feasibility study of QAMS for quantitative analysis of multiple structural types of ingredients in Atractylodis Rhizome by GC]. Zhongguo Zhong Yao Za Zhi. 2018 Feb;43(3):551-556. doi: 10.19540/j.cnki.cjcmm.20180104.011. Chinese. PubMed PMID: 29600621.