MedKoo Cat#: 564782 | Name: Bisindolylmaleimide IV
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bisindolylmaleimide IV is an inhibitor of pyruvate phosphate dikinase (PPDK).

Chemical Structure

Bisindolylmaleimide IV
Bisindolylmaleimide IV
CAS#119139-23-0

Theoretical Analysis

MedKoo Cat#: 564782

Name: Bisindolylmaleimide IV

CAS#: 119139-23-0

Chemical Formula: C20H13N3O2

Exact Mass: 327.1008

Molecular Weight: 327.34

Elemental Analysis: C, 73.38; H, 4.00; N, 12.84; O, 9.78

Price and Availability

Size Price Availability Quantity
100mg USD 350.00 2 Weeks
250mg USD 650.00 2 Weeks
1g USD 1,250.00 2 Weeks
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Related CAS #
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Synonym
Bisindolylmaleimide IV
IUPAC/Chemical Name
3,4-Bis(1H-indol-3-yl)pyrrole-2,5-dione
InChi Key
DQYBRTASHMYDJG-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
SMILES Code
O=C(C(C1=CNC2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 327.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Minges A, Groth G. Small-molecule inhibition of pyruvate phosphate dikinase targeting the nucleotide binding site. PLoS One. 2017 Jul 10;12(7):e0181139. doi: 10.1371/journal.pone.0181139. eCollection 2017. PubMed PMID: 28700696; PubMed Central PMCID: PMC5507339.