Bisindolylmaleimide V | CAS#113963-68-1 | PKC inhibitor

MedKoo Cat#: 563417 | Name: Bisindolylmaleimide V

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bisindolylmaleimide V is a weak inhibitor of protein kinase C (PKC). It acts by blocking the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo.

Chemical Structure

Bisindolylmaleimide V

CAS#113963-68-1

Theoretical Analysis

MedKoo Cat#: 563417

Name: Bisindolylmaleimide V

CAS#: 113963-68-1

Chemical Formula: C21H15N3O2

Exact Mass: 341.1164

Molecular Weight: 341.37

Elemental Analysis: C, 73.89; H, 4.43; N, 12.31; O, 9.37

Price and Availability

Size	Price	Availability	Quantity
250mg	USD 250.00	2 Weeks
1g	USD 550.00	2 Weeks

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Related CAS #

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Synonym

Bisindolylmaleimide V; Bisindolylmaleimide-V; Ro 31-6045; Ro 316045; Ro 31 6045; BIMV; BIM-V; BIM V;

IUPAC/Chemical Name

3,4-Di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione

InChi Key

SWAWYMIKGOHZMR-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H15N3O2/c1-24-20(25)18(14-10-22-16-8-4-2-6-12(14)16)19(21(24)26)15-11-23-17-9-5-3-7-13(15)17/h2-11,22-23H,1H3

SMILES Code

O=C(C(C1=CNC2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)N(C)C3=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 341.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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