MedKoo Cat#: 564760 | Name: ITI-722
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ITI-722 is a first-in-class dual 5HT2A receptor antagonist and dopamine receptor phosphoprotein modulator (DPPM).

Chemical Structure

ITI-722
ITI-722
CAS#313368-91-1 (free base)

Theoretical Analysis

MedKoo Cat#: 564760

Name: ITI-722

CAS#: 313368-91-1 (free base)

Chemical Formula: C24H28FN3O

Exact Mass: 393.2216

Molecular Weight: 393.51

Elemental Analysis: C, 73.26; H, 7.17; F, 4.83; N, 10.68; O, 4.07

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
250mg USD 750.00 2 Weeks
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Synonym
ITI007; ITI-007; ITI007; ITI722; ITI 722; ITI-722
IUPAC/Chemical Name
1-(4-Fluorophenyl)-4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)butan-1-one
InChi Key
HOIIHACBCFLJET-SFTDATJTSA-N
InChi Code
InChI=1S/C24H28FN3O/c1-26-14-15-28-21-11-13-27(16-20(21)19-4-2-5-22(26)24(19)28)12-3-6-23(29)17-7-9-18(25)10-8-17/h2,4-5,7-10,20-21H,3,6,11-16H2,1H3/t20-,21-/m0/s1
SMILES Code
O=C(C1=CC=C(F)C=C1)CCCN2CC[C@@](N3CCN(C)C4=C3C5=CC=C4)([H])[C@@]5([H])C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 393.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kumar B, Kuhad A, Kuhad A. Lumateperone: a new treatment approach for neuropsychiatric disorders. Drugs Today (Barc). 2018 Dec;54(12):713-719. doi: 10.1358/dot.2018.54.12.2899443. PubMed PMID: 30596390.