Synonym
Lysine salicylate
IUPAC/Chemical Name
L-Lysine, 2-hydroxybenzoate
InChi Key
KZBKRARRXDZOII-ZSCHJXSPSA-N
InChi Code
InChI=1S/C7H6O3.C6H14N2O2/c8-6-4-2-1-3-5(6)7(9)10;7-4-2-1-3-5(8)6(9)10/h1-4,8H,(H,9,10);5H,1-4,7-8H2,(H,9,10)/t;5-/m.0/s1
SMILES Code
N[C@@H](CCCCN)C(O)=O.O=C(O)C1=CC=CC=C1O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
284.31
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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5: Rothschild AM. Endosprin, an antipyretic, antiinflammatory and analgesic preparation of lysine salicylate: reassessment of its chemical composition and effects in experimental animals in comparison with aspirin. Braz J Med Biol Res. 1984;17(2):185-8. PubMed PMID: 6440612.
6: Launo C, Molinino M, Bassi C, Carbone M, Novielli N. [Postoperative analgesia with lysine salicylate and pentazocine]. Minerva Anestesiol. 1981 May;47(5):237-40. Italian. PubMed PMID: 6793924.
7: Blendinger I, Eberlein HJ. Comparison of intravenous acetylsalicylic acid and dipyrone in postoperative pain: an interim report. Br J Clin Pharmacol. 1980 Oct;10 Suppl 2:339S-341S. PubMed PMID: 7437274; PubMed Central PMCID: PMC1430189.
