MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 207003 | Name: RV6153

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RV6153 is an PI3K inhibitor.

Chemical Structure

RV6153
RV6153
CAS#1628139-03-6

Theoretical Analysis

MedKoo Cat#: 207003

Name: RV6153

CAS#: 1628139-03-6

Chemical Formula: C36H31F4N7O5

Exact Mass: 717.2323

Molecular Weight: 717.68

Elemental Analysis: C, 60.25; H, 4.35; F, 10.59; N, 13.66; O, 11.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
RV6153; RV-6153; RV 6153;
IUPAC/Chemical Name
2-((4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-(3-(2-(2-methoxyethoxy)ethoxy)prop-1-yn-1-yl)-3-(2-(trifluoromethyl)benzyl)quinazolin-4(3H)-one
InChi Key
JTACVHJPXOKMTI-UHFFFAOYSA-N
InChi Code
InChI=1S/C36H31F4N7O5/c1-50-12-13-52-15-14-51-11-5-8-22-7-4-10-28-30(22)35(49)46(19-23-6-2-3-9-27(23)36(38,39)40)29(44-28)20-47-34-31(33(41)42-21-43-34)32(45-47)24-16-25(37)18-26(48)17-24/h2-4,6-7,9-10,16-18,21,48H,11-15,19-20H2,1H3,(H2,41,42,43)
SMILES Code
FC(F)(C1=CC=CC=C1CN2C(CN3N=C(C4=C(N=CN=C43)N)C5=CC(F)=CC(O)=C5)=NC6=C(C(C#CCOCCOCCOC)=CC=C6)C2=O)F
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 717.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Evolution of PI3Kγ and δ Inhibitors for Inflammatory and Autoimmune Diseases Matthew W. D. Perry, Raolat Abdulai, Mickael Mogemark, Jens Petersen, Matthew J. Thomas, Barbara Valastro, and Annika Westin Eriksson Publication Date (Web): December 24, 2018 (Perspective); DOI: 10.1021/acs.jmedchem.8b01298

View History

BW 540C

BW 540C